Studies of the genetic basis of behaviour in mice are at a turning point. Soon, new resources will enable the behavioural function of all genes to be tested and the networks of genes, messenger RNAs and proteins involved in a particular behaviour to be identified. Using these resources, scientists will be able to analyse mouse behaviour at an unprecedented level of detail. Interpreting the new data, however, will require a shift in focus from gene-based approaches to network-based approaches
Full genome sequencing, high-density genotyping, expanding sets of microarray assays, and systematic...
The historical origins of classical laboratory mouse strains have led to a relatively limited range ...
I survey the state of the art in complex trait analysis, including the use of new experimental and c...
Studies of the genetic basis of behaviour in mice are at a turning point. Soon, new resources will e...
This chapter describes a use case for the genetic dissection and automated analysis of complex behav...
Recent advances in systems genetics and integrative functional genomics have greatly improved the st...
Understanding the genetics of behavioral variation remains a fascinating but difficult problem with ...
Identifying genes and pathways that contribute to differences in neurobehavioural traits is a key go...
The mouse has been a powerful force in elucidating the genetic basis of human physiology and pathoph...
It seems that the genetic basis of common psychiatric diseases such as schizophrenia and manic-depre...
Genome-wide association studies (GWAS) have emerged as a powerful tool to identify alleles and molec...
Progress in complex trait mapping in mice has been accelerated by the development of new populations...
The complicated interactions between genetic background, environment and lifestyle factors make it d...
Mood disorders have powerful effects on the lives of many people. Finding the mechanisms underlying ...
Behavioral differences between inbred strains of mice and rats have a genetic basis that can now be ...
Full genome sequencing, high-density genotyping, expanding sets of microarray assays, and systematic...
The historical origins of classical laboratory mouse strains have led to a relatively limited range ...
I survey the state of the art in complex trait analysis, including the use of new experimental and c...
Studies of the genetic basis of behaviour in mice are at a turning point. Soon, new resources will e...
This chapter describes a use case for the genetic dissection and automated analysis of complex behav...
Recent advances in systems genetics and integrative functional genomics have greatly improved the st...
Understanding the genetics of behavioral variation remains a fascinating but difficult problem with ...
Identifying genes and pathways that contribute to differences in neurobehavioural traits is a key go...
The mouse has been a powerful force in elucidating the genetic basis of human physiology and pathoph...
It seems that the genetic basis of common psychiatric diseases such as schizophrenia and manic-depre...
Genome-wide association studies (GWAS) have emerged as a powerful tool to identify alleles and molec...
Progress in complex trait mapping in mice has been accelerated by the development of new populations...
The complicated interactions between genetic background, environment and lifestyle factors make it d...
Mood disorders have powerful effects on the lives of many people. Finding the mechanisms underlying ...
Behavioral differences between inbred strains of mice and rats have a genetic basis that can now be ...
Full genome sequencing, high-density genotyping, expanding sets of microarray assays, and systematic...
The historical origins of classical laboratory mouse strains have led to a relatively limited range ...
I survey the state of the art in complex trait analysis, including the use of new experimental and c...