Add to ORKGIn the last years, valuable data about the biology and pharmacology of cancer-related human proteins have been provided by our research group using yeast. Furthermore, new targets and pharmacological regulators of these human proteins were identified. Also, new yeast target-based screening assays were developed, which revealed to be powerful tools in the discovery of new therapeutic opportunities against cancer
Determining the protein target(s) and mechanism(s) of drug candidates found in phenotypic screens is...
Programmed cell death (PCD) plays an important role in development and normal metabolic functioning ...
AbstractIn order to alter the impact of diseases on human society, drug development has been one of ...
The ability to precisely engineer yeast, coupled with its genetic and metabolic similarity to tumor ...
Cancer is a devastating disease with a profound impact on society. In recent years, yeast has provid...
The budding yeast Saccharomyces cerevisiae is a valuable system to study cell-cycle regulation, whic...
AbstractThe budding yeast Saccharomyces cerevisiae is a genetically tractable model system with whic...
AbstractA study in this issue of Cell illustrates the power of applying genomic approaches with mode...
In this study the mitochondrion is regarded as a target to reveal compounds that may be used to comb...
Recombinant DNA technology made possible exciting new uses for yeasts as it did for various other or...
When the glucose supply is high, despite the presence of oxygen, Saccharomyces cerevisiae uses ferme...
When the glucose supply is high, despite the presence of oxygen, Saccharomyces cerevisiae uses ferme...
Yeast cells can be killed upon expression of pro-apoptotic mammalian proteins. We have established a...
During tumour progression, cells accumulate secondary mutations and/or chromosomal aberrations that ...
<div><p>Yeast cells can be killed upon expression of pro-apoptotic mammalian proteins. We have estab...
Determining the protein target(s) and mechanism(s) of drug candidates found in phenotypic screens is...
Programmed cell death (PCD) plays an important role in development and normal metabolic functioning ...
AbstractIn order to alter the impact of diseases on human society, drug development has been one of ...
The ability to precisely engineer yeast, coupled with its genetic and metabolic similarity to tumor ...
Cancer is a devastating disease with a profound impact on society. In recent years, yeast has provid...
The budding yeast Saccharomyces cerevisiae is a valuable system to study cell-cycle regulation, whic...
AbstractThe budding yeast Saccharomyces cerevisiae is a genetically tractable model system with whic...
AbstractA study in this issue of Cell illustrates the power of applying genomic approaches with mode...
In this study the mitochondrion is regarded as a target to reveal compounds that may be used to comb...
Recombinant DNA technology made possible exciting new uses for yeasts as it did for various other or...
When the glucose supply is high, despite the presence of oxygen, Saccharomyces cerevisiae uses ferme...
When the glucose supply is high, despite the presence of oxygen, Saccharomyces cerevisiae uses ferme...
Yeast cells can be killed upon expression of pro-apoptotic mammalian proteins. We have established a...
During tumour progression, cells accumulate secondary mutations and/or chromosomal aberrations that ...
<div><p>Yeast cells can be killed upon expression of pro-apoptotic mammalian proteins. We have estab...
Determining the protein target(s) and mechanism(s) of drug candidates found in phenotypic screens is...
Programmed cell death (PCD) plays an important role in development and normal metabolic functioning ...
AbstractIn order to alter the impact of diseases on human society, drug development has been one of ...