Adoptive cellular therapies are gaining popularity as a means to treat clinical conditions, with potentially fewer risks and greater efficacy than traditional pharmacological strategies. Regulatory T cells (Tregs) are currently undergoing clinical trials in various immune-mediated pathologies, including transplant rejection and autoimmune conditions. In general, cell therapy relies upon ex vivo expansion of the cell product, in order to administer more cells than can be isolated from one person. In vitro manipulation of cell therapy products, prior to administration to patients, offers the opportunity to enhance the efficacy of the final cell therapy product in other ways. For example, cells can be exposed to reagents that enhance their lon...
Regulatory T cells (Tregs) are essential to transplantation tolerance and their therapeutic efficacy...
Cell-based immunotherapies address a number of unmet medical needs and some have shown success. All ...
Regulatory T cells (Treg cells) are a small subset of immune cells that are dedicated to curbing exc...
Adoptive cellular therapies are gaining popularity as a means to treat clinical conditions, with pot...
Background: A growing number of clinical trials have shown that regulatory T (Treg) cell transfer ma...
Regulatory T cells (Tregs) control unwanted immune responses, including those that mediate tolerance...
Regulatory T cells (Tregs) are essential to transplantation tolerance and their therapeutic efficacy...
The use of adoptively-transferred regulatory T cell (Tregs) for the treatment of graft-versus-host d...
Solid organ transplantation has evolved from being an experimental procedure to a life-saving treatm...
Cellular therapies using regulatory T (Treg) cells are currently undergoing clinical trials for the ...
Regulatory T cells (Tregs) have enormous therapeutic potential to treat a variety of immunopathologi...
Engineered T cells are currently in clinical trials to treat patients with cancer, solid organ trans...
BackgroundTherapies directed at augmenting regulatory T cell (Treg) activities in vivo as a systemic...
International audienceOrgan or cell transplantation is the only therapeutic solution for pathologies...
Regulatory T cells (Tregs) are CD4+ T cells that are key players of immune tolerance. They are power...
Regulatory T cells (Tregs) are essential to transplantation tolerance and their therapeutic efficacy...
Cell-based immunotherapies address a number of unmet medical needs and some have shown success. All ...
Regulatory T cells (Treg cells) are a small subset of immune cells that are dedicated to curbing exc...
Adoptive cellular therapies are gaining popularity as a means to treat clinical conditions, with pot...
Background: A growing number of clinical trials have shown that regulatory T (Treg) cell transfer ma...
Regulatory T cells (Tregs) control unwanted immune responses, including those that mediate tolerance...
Regulatory T cells (Tregs) are essential to transplantation tolerance and their therapeutic efficacy...
The use of adoptively-transferred regulatory T cell (Tregs) for the treatment of graft-versus-host d...
Solid organ transplantation has evolved from being an experimental procedure to a life-saving treatm...
Cellular therapies using regulatory T (Treg) cells are currently undergoing clinical trials for the ...
Regulatory T cells (Tregs) have enormous therapeutic potential to treat a variety of immunopathologi...
Engineered T cells are currently in clinical trials to treat patients with cancer, solid organ trans...
BackgroundTherapies directed at augmenting regulatory T cell (Treg) activities in vivo as a systemic...
International audienceOrgan or cell transplantation is the only therapeutic solution for pathologies...
Regulatory T cells (Tregs) are CD4+ T cells that are key players of immune tolerance. They are power...
Regulatory T cells (Tregs) are essential to transplantation tolerance and their therapeutic efficacy...
Cell-based immunotherapies address a number of unmet medical needs and some have shown success. All ...
Regulatory T cells (Treg cells) are a small subset of immune cells that are dedicated to curbing exc...