Mutation analysis of three genes encoding novel LKB1-interacting proteins, BRG1, STRADalpha, and MO25alpha, in Peutz-Jeghers syndrome.
- Alhopuro, P
- Katajisto, P
- Lehtonen, R
- Ylisaukko-Oja, SK
- Näätsaari, L
- Karhu, A
- Westerman, AM
- Wilson, JH
- de Rooij, FW
- Vogel, T
- Moeslein, G
- Tomlinson, IP
- Aaltonen, LA
- Mäkelä, TP
- Launonen, V
Publication date
March 2005
DOI Publisher
Springer Science and Business Media LLC Journal
British Journal of CancerAbstract
Mutations in LKB1 lead to Peutz-Jeghers syndrome (PJS). However, only a subset of PJS patients harbours LKB1 mutations. We performed a mutation analysis of three genes encoding novel LKB1-interacting proteins, BRG1, STRADalpha, and MO25alpha, in 28 LKB1-negative PJS patients. No disease-causing mutations were detected in the studied genes in PJS patients from different European populations
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