[reaction: see text] The first synthesis of the pyrrolidinone core of the polyene beta-lactone antibiotic KSM-2690 B is described. An ammonia-free Birch reductive aldol reaction utilizing acetaldehyde is one of the key steps, together with a ruthenium-catalyzed alkene isomerization reaction
This thesis is concerned with the development of novel routes to the pyrrolidine trans-lactams 246, ...
Salinosporamide A, a highly bioactive [beta]-lactone from the marine bacterium Salinispora tropica, ...
Also book chapter: An Adventure in Synthesis Inspired by the Pseudolaric Acids. In M. Harmata (Eds.)...
The asymmetric synthesis of the key pyrrolidinone core, including a highly elaborated exocyclic carb...
[reaction; see text] N-Boc syn-7-(2-hydroxyethyl)-4-(alkyl or aryl)sulfonyl-2-azabicyclo[2.2.1]hept-...
[Structure: see text] Key reactions in a concise synthesis of an alpha-C-galactosylceramide analogue...
A new synthesis of the 20S proteasome inhibitor clasto-lactacystin beta-lactone is described. Our ro...
A key step in the synthesis of lactacystin β-lactone (3), an inhibitor of the 20 S proteasome, was t...
This thesis describes the development of synthetic strategies towards the densely functionalised pyr...
Michael addition of malononitrile as nucleophiles to nitroalkenes as electrophiles has been scarcely...
The prostaglandins are a unique family of natural products found in all mammalian life, including hu...
The thesis describes the synthesis and application of various alkynones derived from the bis-Weinreb...
[reaction: see text] The synthesis of the highly strained 3-aza-[7]-paracyclophane core of haouamine...
The preparation and reactivity of β-lactones is discussed and is followed by a review of the biologi...
In past years, students in organic chemistry II lab (Chem 331L) at Gonzaga University have synthesiz...
This thesis is concerned with the development of novel routes to the pyrrolidine trans-lactams 246, ...
Salinosporamide A, a highly bioactive [beta]-lactone from the marine bacterium Salinispora tropica, ...
Also book chapter: An Adventure in Synthesis Inspired by the Pseudolaric Acids. In M. Harmata (Eds.)...
The asymmetric synthesis of the key pyrrolidinone core, including a highly elaborated exocyclic carb...
[reaction; see text] N-Boc syn-7-(2-hydroxyethyl)-4-(alkyl or aryl)sulfonyl-2-azabicyclo[2.2.1]hept-...
[Structure: see text] Key reactions in a concise synthesis of an alpha-C-galactosylceramide analogue...
A new synthesis of the 20S proteasome inhibitor clasto-lactacystin beta-lactone is described. Our ro...
A key step in the synthesis of lactacystin β-lactone (3), an inhibitor of the 20 S proteasome, was t...
This thesis describes the development of synthetic strategies towards the densely functionalised pyr...
Michael addition of malononitrile as nucleophiles to nitroalkenes as electrophiles has been scarcely...
The prostaglandins are a unique family of natural products found in all mammalian life, including hu...
The thesis describes the synthesis and application of various alkynones derived from the bis-Weinreb...
[reaction: see text] The synthesis of the highly strained 3-aza-[7]-paracyclophane core of haouamine...
The preparation and reactivity of β-lactones is discussed and is followed by a review of the biologi...
In past years, students in organic chemistry II lab (Chem 331L) at Gonzaga University have synthesiz...
This thesis is concerned with the development of novel routes to the pyrrolidine trans-lactams 246, ...
Salinosporamide A, a highly bioactive [beta]-lactone from the marine bacterium Salinispora tropica, ...
Also book chapter: An Adventure in Synthesis Inspired by the Pseudolaric Acids. In M. Harmata (Eds.)...