Severe anemia in Malawian children.
- Calis, JC
- Phiri, KS
- Faragher, EB
- Brabin, BJ
- Bates, I
- Cuevas, LE
- de Haan, RJ
- Phiri, AI
- Malange, P
- Khoka, M
- Hulshof, PJ
- van Lieshout, L
- Beld, MG
- Teo, YY
- Rockett, KA
- Richardson, A
- Kwiatkowski, DP
- Molyneux, ME
- van Hensbroek, MB
DOIAbstract
BACKGROUND: Severe anemia is a major cause of sickness and death in African children, yet the causes of anemia in this population have been inadequately studied. METHODS: We conducted a case-control study of 381 preschool children with severe anemia (hemoglobin concentration, <5.0 g per deciliter) and 757 preschool children without severe anemia in urban and rural settings in Malawi. Causal factors previously associated with severe anemia were studied. The data were examined by multivariate analysis and structural equation modeling. RESULTS: Bacteremia (adjusted odds ratio, 5.3; 95% confidence interval [CI], 2.6 to 10.9), malaria (adjusted odds ratio, 2.3; 95% CI, 1.6 to 3.3), hookworm (adjusted odds ratio, 4.8; 95% CI, 2.0 to 11.8), human ...
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