The results of radiotherapy of head and neck tumors. Comparison of conformal radiotherapy and IMRT

Malignant tumors of the head and neck are globally around 5 % of all malignant tumors. To the group of tumors of the head and neck falls oral cavity, pharynx, larynx, nasal cavity, paranasal sinuses, and salivary glands. The main treatment modalities are included surgical treatment, radiotherapy, chemotherapy and biotherapy. The first aim of this thesis was to compare the results of radiotherapy of tumors of the head and neck in a hospital in Ceske Budejovice with specialised literature.The second objective was to compare conformal and IMRT techniques within the meaning of recurrences.Data collection was conducted in patients diagnosed with tumor of the oral cavity and pharynx during years 2004 to 2010. When comparing treatment results with data from the first scientific literature with the results monitored group agree on decreasing tendency on five-year survival with increasing degree of the stadium. When comparing five-year survival rate for tumors of the oral cavity with the reference group of patients with data from the other specialised literature, correspondence does not exist.In this case, the hypothesis can not be confirmed. In the second set hypothesis it was assumed that the lower incidence of relapses occur after irradiation by the technique IMRT. Although the hypothesis was confirmed,although the gap between the technology 3D-CRT and IMRT for recurrences is tiny, only tenths.A crucial factor influencing survival is the time of diagnosis. Improving this fact could be achieved by appropriate preventive programs, which are targeted primarily at risk group of people