Prediction of thermodynamic loss in transitional boundary layers is typically based on time-averaged data only. This approach effectively ignores the intermittent nature of the transition region. In this work laminar and turbulent conditionally sampled boundary layer data for zero pressure gradient and accelerating transitional boundary layers have been analyzed to calculate the entropy generation rate in the transition region. By weighting the nondimensional dissipation coefficient for the laminar conditioned data and turbulent conditioned data with the intermittency factor, the entropy generation rate in the transition region can be determined and compared to the time-averaged data and correlations for laminar and turbulent flow. It is de...