Dieting is a widespread behaviour in developed countries, which in predisposed individuals can lead to the development of clinical eating disorders such as bulimia nervosa and anorexia nervosa. We studied the effect of moderate dieting in healthy women on the prolactin response to the serotonin (5-HT) receptor agonist, m-chlorophenylpiperazine (mCPP), a measure of the sensitivity of post-synaptic 5-HT2C receptors. Dieting significantly increased the prolactin response to mCPP and lowered plasma concentrations of the 5-HT precursor, tryptophan. We propose that dieting in women is associated with the development of functional supersensitivity of 5-HT2C receptors, probably in response to lowered levels of brain 5-HT. Alterations in brain 5-HT ...
Although obesity is a global epidemic, the physiological mechanisms involved are not well understood...
SummaryThe neural pathways through which central serotonergic systems regulate food intake and body ...
The central serotonergic signalling system has been shown to play an important role in appetite cont...
Dieting is a widespread behaviour in developed countries, which in predisposed individuals can lead ...
The increase in plasma prolactin which follows intravenous administration of L-tryptophan (LTP) was ...
Dieting is a common behaviour which may trigger eating disorders such as bulimia nervosa in predispo...
Rationale Brain 5-HT2C receptors form part of a neural network that controls eating behaviour. 5-HT...
We studied the effect of 2 weeks administration of the 5-HT2C receptor agonist, m-chlorophenylpipera...
We studied the effect of the 5-HT receptor agonist, m-chlorophenylpiperazine (mCPP) (0.4 mg/kg), on ...
The past two decades have seen an upturn in interest in the psychiatric disorders anorexia and bulim...
BACKGROUND: Amino acid mixtures that lower brain availability of the serotonin (5-HT) precursor tryp...
Serotonin has been implicated in the control of satiety for almost four decades. Historically, the i...
Low tryptophan (TRP) diets decrease brain serotonin (5-HT) content and produce an up-regulation of t...
The central serotonergic signalling system has been shown to play an important role in appetite cont...
The central serotonergic signalling system has been shown to play an important role in appetite cont...
Although obesity is a global epidemic, the physiological mechanisms involved are not well understood...
SummaryThe neural pathways through which central serotonergic systems regulate food intake and body ...
The central serotonergic signalling system has been shown to play an important role in appetite cont...
Dieting is a widespread behaviour in developed countries, which in predisposed individuals can lead ...
The increase in plasma prolactin which follows intravenous administration of L-tryptophan (LTP) was ...
Dieting is a common behaviour which may trigger eating disorders such as bulimia nervosa in predispo...
Rationale Brain 5-HT2C receptors form part of a neural network that controls eating behaviour. 5-HT...
We studied the effect of 2 weeks administration of the 5-HT2C receptor agonist, m-chlorophenylpipera...
We studied the effect of the 5-HT receptor agonist, m-chlorophenylpiperazine (mCPP) (0.4 mg/kg), on ...
The past two decades have seen an upturn in interest in the psychiatric disorders anorexia and bulim...
BACKGROUND: Amino acid mixtures that lower brain availability of the serotonin (5-HT) precursor tryp...
Serotonin has been implicated in the control of satiety for almost four decades. Historically, the i...
Low tryptophan (TRP) diets decrease brain serotonin (5-HT) content and produce an up-regulation of t...
The central serotonergic signalling system has been shown to play an important role in appetite cont...
The central serotonergic signalling system has been shown to play an important role in appetite cont...
Although obesity is a global epidemic, the physiological mechanisms involved are not well understood...
SummaryThe neural pathways through which central serotonergic systems regulate food intake and body ...
The central serotonergic signalling system has been shown to play an important role in appetite cont...