Markers of inflammation: data from the MOSAIC randomised trial of CPAP for minimally symptomatic OSA
- Stradling, JR
- Craig, SE
- Kohler, M
- Nicoll, D
- Ayers, L
- Nunn, AJ
- Bratton, DJ
DOIAbstract
The Multi-centre Obstructive Sleep Apnoea Interventional Cardiovascular (MOSAIC) trial compared 6 months of CPAP therapy, versus no CPAP, in 391 patients with minimally symptomatic obstructive sleep apnoea (OSA). We now report some exploratory outcomes, markers of systemic inflammation (interleukin 6 (IL-6), IL-10, C reactive protein, tumour necrosis factor). We found no consistent changes (all p values >0.13).ISRCTN 34164388
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