Differences in lymphocyte morfology of children and adults

Lymphocytes belong among white blood cells and they are involved in the body defense reactions. With other cells they create the human immunity system. In blood counts they are included in the differential leukocyte budget. Morphology of lymphocytes is evaluated in the microscope. The evaluation of morphology is an important aspect in distinguishing a normal state from a state that is caused by infection or hematological diagnosis. In this dissertation I will be dealing with the percentage of lymphocytes in the peripheral blood from birth to adulthood, measuring cell size and morphology evaluation of four types of cells: normal lymphocytes, atypical small lymphocytes which resemble "hematogones" , atypical large reactive lymphocytes with nucleus changes and esp. in the cytoplasm and and large granular lymphocytes (ie. LGL). On each lymphocyte I also used special staining for visualisation of the nucleoli for evaluation of three types of them - ringed, large and micronucleoli and number of nucleoli in cells. The purpose of this work is a microscopic comparison of the number of lymphocytes, their size, type and type of nucleus as it varies depending at the age from birth to adulthood