Tremor can dominate Parkinson's disease and yet responds less well to dopaminergic medications than do other cardinal symptoms of this condition. Deep brain stimulation can provide striking tremor relief, but the introduction of stimulating electrodes deep in the substance of the brain carries significant risks, including those of hemorrhage. Here, we pioneer an alternative approach in which we noninvasively apply transcranial alternating current stimulation (TACS) over the motor cortex to induce phase cancellation of the rest tremor rhythm. We first identify the timing of cortical oscillations responsible for rest tremor in the periphery by delivering tremor-frequency stimulation over motor cortex but do not couple this stimulation to the ...
Background Resting tremor is one of the most common symptoms of Parkinson’s disease. Despite its hig...
Pathological tremors are involuntary oscillatory movements which cannot be fully attenuated using co...
Transcranial alternating current stimulation (tACS) is a noninvasive neuromodulation method that can...
Tremor can dominate Parkinson's disease and yet responds less well to dopaminergic medications than ...
Tremor can dominate Parkinson's disease and yet responds less well to dopaminergic medications than ...
SummaryTremor can dominate Parkinson’s disease and yet responds less well to dopaminergic medication...
SummaryTremor can dominate Parkinson’s disease and yet responds less well to dopaminergic medication...
See Moll and Engel (doi:10.1093/aww308) for a scientific commentary on this article Brain regions dy...
SEE MOLL AND ENGEL DOI101093/AWW308 FOR A SCIENTIFIC COMMENTARY ON THIS ARTICLE: Brain regions dynam...
High frequency deep brain stimulation of the thalamus can help ameliorate severe essential tremor. H...
High frequency deep brain stimulation of the thalamus can help ameliorate severe essential tremor. H...
High frequency deep brain stimulation of the thalamus can help ameliorate severe essential tremor. H...
Objective: To establish the causal role of the cerebellum and motor cortex in dystonic tremor syndro...
High frequency deep brain stimulation of the thalamus can help ameliorate severe essential tremor. H...
Resting tremor in Parkinson’s disease (PD) affects quality of life and individuals’ ability to compl...
Background Resting tremor is one of the most common symptoms of Parkinson’s disease. Despite its hig...
Pathological tremors are involuntary oscillatory movements which cannot be fully attenuated using co...
Transcranial alternating current stimulation (tACS) is a noninvasive neuromodulation method that can...
Tremor can dominate Parkinson's disease and yet responds less well to dopaminergic medications than ...
Tremor can dominate Parkinson's disease and yet responds less well to dopaminergic medications than ...
SummaryTremor can dominate Parkinson’s disease and yet responds less well to dopaminergic medication...
SummaryTremor can dominate Parkinson’s disease and yet responds less well to dopaminergic medication...
See Moll and Engel (doi:10.1093/aww308) for a scientific commentary on this article Brain regions dy...
SEE MOLL AND ENGEL DOI101093/AWW308 FOR A SCIENTIFIC COMMENTARY ON THIS ARTICLE: Brain regions dynam...
High frequency deep brain stimulation of the thalamus can help ameliorate severe essential tremor. H...
High frequency deep brain stimulation of the thalamus can help ameliorate severe essential tremor. H...
High frequency deep brain stimulation of the thalamus can help ameliorate severe essential tremor. H...
Objective: To establish the causal role of the cerebellum and motor cortex in dystonic tremor syndro...
High frequency deep brain stimulation of the thalamus can help ameliorate severe essential tremor. H...
Resting tremor in Parkinson’s disease (PD) affects quality of life and individuals’ ability to compl...
Background Resting tremor is one of the most common symptoms of Parkinson’s disease. Despite its hig...
Pathological tremors are involuntary oscillatory movements which cannot be fully attenuated using co...
Transcranial alternating current stimulation (tACS) is a noninvasive neuromodulation method that can...