Add to ORKGTyphoid fever causes more than 21 million cases of disease and 200,000 deaths yearly worldwide, with more than 90% of the disease burden being reported from Asia. Epidemiological data show high disease incidence in young children and suggest that immunization programs should target children below two years of age: this is not possible with available vaccines. The Novartis Vaccines Institute for Global Health developed a conjugate vaccine (Vi-CRM₁₉₇) for infant vaccination concomitantly with EPI vaccines, either starting at 6 weeks with DTP or at 9 months with measles vaccine. We report the results from a Phase 1 and a Phase 2 dose ranging trial with Vi-CRM₁₉₇ in European adults
Background: Typhoid fever remains a major public health problem globally. While new Vi conjugate vac...
Typhoid fever illnesses are responsible for more than 100 000 deaths worldwide each year. In Banglad...
Typhoid fever is an acute systemic infectious disease responsible for an estimated 12-20 million ill...
Background: Typhoid fever causes more than 21 million cases of disease and 200,000 deaths yearly wor...
Background: Typhoid vaccination is a public health priority in developing countries where young chil...
IntroductionThere is a high global incidence of typhoid fever, with an annual mortality rate of 200,...
in European adults. (1·25 µg, 5·0 µg and 12·5 µg of Vi antigen) with the polysaccharide vaccine. fo...
IntroductionThere is a high global incidence of typhoid fever, with an annual mortality rate of 200,...
Typhoid fever remains a serious problem in developing countries. Current vaccines are licensed for i...
Each year, 12.1 to 20.6 million typhoid fever infections occur globally, of which 1% result in death...
Typhoid fever remains to be a serious disease burden worldwide with an estimated annual incidence ab...
BACKGROUND:Typhoid fever remains a significant cause of morbidity and mortality in developing countr...
Globally, an estimated 11 to 21 million cases of febrile illness and 117,000 to 161,000 deaths are a...
Background Enteric fever is estimated to affect 11–20 million people worldwide each year. Morbidity ...
Background Typhoid fever and paratyphoid fever continue to be important causes of illness and dea...
Background: Typhoid fever remains a major public health problem globally. While new Vi conjugate vac...
Typhoid fever illnesses are responsible for more than 100 000 deaths worldwide each year. In Banglad...
Typhoid fever is an acute systemic infectious disease responsible for an estimated 12-20 million ill...
Background: Typhoid fever causes more than 21 million cases of disease and 200,000 deaths yearly wor...
Background: Typhoid vaccination is a public health priority in developing countries where young chil...
IntroductionThere is a high global incidence of typhoid fever, with an annual mortality rate of 200,...
in European adults. (1·25 µg, 5·0 µg and 12·5 µg of Vi antigen) with the polysaccharide vaccine. fo...
IntroductionThere is a high global incidence of typhoid fever, with an annual mortality rate of 200,...
Typhoid fever remains a serious problem in developing countries. Current vaccines are licensed for i...
Each year, 12.1 to 20.6 million typhoid fever infections occur globally, of which 1% result in death...
Typhoid fever remains to be a serious disease burden worldwide with an estimated annual incidence ab...
BACKGROUND:Typhoid fever remains a significant cause of morbidity and mortality in developing countr...
Globally, an estimated 11 to 21 million cases of febrile illness and 117,000 to 161,000 deaths are a...
Background Enteric fever is estimated to affect 11–20 million people worldwide each year. Morbidity ...
Background Typhoid fever and paratyphoid fever continue to be important causes of illness and dea...
Background: Typhoid fever remains a major public health problem globally. While new Vi conjugate vac...
Typhoid fever illnesses are responsible for more than 100 000 deaths worldwide each year. In Banglad...
Typhoid fever is an acute systemic infectious disease responsible for an estimated 12-20 million ill...