Add to ORKGThe synthesis and preliminary structure-activity relationship of a series of pyrrolidinones are described. These pyrrolidinones have been characterized as novel non-nucleoside reverse transcriptase inhibitors (NNRTIs) which are highly potent against wild-type and drug-resistant human immunodeficiency viruses (HIV-1)
This paper reports the synthesis and the antiviral properties of new diarylpyrimidine (DAPY) compoun...
Novel compounds 1a-u, which can be considered as hybrid analogues of MKC-442 and pyridinon, have bee...
A novel series of substituted piperazine-1-yl-pyrimidine derivatives were designed and synthesized a...
Novel 6-substituted-4-cycloalkyloxy-pyridin-2(1H)-ones were synthesized as non-nucleoside reverse tr...
A series of novel pyrazinones designed as non-nucleoside reverse transcriptase inhibitors (NNRTIs) w...
A novel 2-pyridinone scaffold was rationally designed and synthesized based on the active anti-HIV a...
Several 5-ethyl-6-methyl-4-cycloalkyloxy-pyridin-2(1<i>H</i>)-ones were synthesized and evaluated fo...
HIV-1 nonnucleoside reverse transcriptase inhibitors (NNRTIs) are part of the combination therapy cu...
This article reports the design, synthesis and antiviral evaluation of a new series of non-nucleosid...
Novel 6-substituted-4-cycloalkyloxy-pyridin-2(1<i>H</i>)-ones were synthesized as non-nucleoside re...
The present work is an extension of our ongoing efforts towards the development and identification o...
In continuation of our efforts toward identification and optimization of novel non-nucleoside revers...
A new series of 29 diarylpyrimidine analogues featuring a cyclopropylamino group between the pyrimid...
A series of novel 5-alkyl-6-Adamantylmethylpyrimidin-4(3H)-ones bearing various substituents at the ...
As a continuation of our efforts to discover and develop "me-better" drugs of DAPYs, novel diarylpyr...
This paper reports the synthesis and the antiviral properties of new diarylpyrimidine (DAPY) compoun...
Novel compounds 1a-u, which can be considered as hybrid analogues of MKC-442 and pyridinon, have bee...
A novel series of substituted piperazine-1-yl-pyrimidine derivatives were designed and synthesized a...
Novel 6-substituted-4-cycloalkyloxy-pyridin-2(1H)-ones were synthesized as non-nucleoside reverse tr...
A series of novel pyrazinones designed as non-nucleoside reverse transcriptase inhibitors (NNRTIs) w...
A novel 2-pyridinone scaffold was rationally designed and synthesized based on the active anti-HIV a...
Several 5-ethyl-6-methyl-4-cycloalkyloxy-pyridin-2(1<i>H</i>)-ones were synthesized and evaluated fo...
HIV-1 nonnucleoside reverse transcriptase inhibitors (NNRTIs) are part of the combination therapy cu...
This article reports the design, synthesis and antiviral evaluation of a new series of non-nucleosid...
Novel 6-substituted-4-cycloalkyloxy-pyridin-2(1<i>H</i>)-ones were synthesized as non-nucleoside re...
The present work is an extension of our ongoing efforts towards the development and identification o...
In continuation of our efforts toward identification and optimization of novel non-nucleoside revers...
A new series of 29 diarylpyrimidine analogues featuring a cyclopropylamino group between the pyrimid...
A series of novel 5-alkyl-6-Adamantylmethylpyrimidin-4(3H)-ones bearing various substituents at the ...
As a continuation of our efforts to discover and develop "me-better" drugs of DAPYs, novel diarylpyr...
This paper reports the synthesis and the antiviral properties of new diarylpyrimidine (DAPY) compoun...
Novel compounds 1a-u, which can be considered as hybrid analogues of MKC-442 and pyridinon, have bee...
A novel series of substituted piperazine-1-yl-pyrimidine derivatives were designed and synthesized a...