Synthesis, characterization and biological activity studies of chalcones derivatives

Two different pathways of etherification on chaIcones' derivatives were studied. A series of alkyl halide consisting of C3, C4, Cs carbon chain were introduced to the starting materials prior to the synthesis of chaIcones' derivatives or vice versa. The yield obtained was calculated and the best pathway was suggested. All the etherified compounds were analyzed by FT-IR and CHN and tested for antibacterial activity against common E. coli. The preliminary antibacterial test showed that all compounds exhibited antibacterial activities to a certain extent against E. coli