Reminders and Negative Reinforcement in Intervention for Medication Adherence

Medication adherence is a critical factor to promote healthcare outcomes, especially for chronic medical conditions. Several mobile health (m-health) interventions have been proposed to increase medication adherence. This research provides design principles of multiple reminders in an intervention to keep medication’s effectiveness and prevent patients from overdosing. Also, this research discusses multiple scenarios of implementation of negative reinforcement (NR) in the intervention design and evaluates the scenarios using analytical modeling. The results provide basic validation of NR in an intervention for medication adherence