The objective is to evaluate the ability of aminoacyl-tRNA synthetases (aaRS) to recognize the non-standard nucleic acid, PNA (peptide nucleic acid). PNA has immense potential in biomedical applications due to its increased thermostability and nuclease resistance over natural nucleic acids. PNA represents a superior alternative to natural nucleic acids in many biomedical applications due to its specificity, strong binding, and nuclease resistance. This study is the initial data set that indicates PNA are recognized by translation enzymes
Peptide nucleic acids (PNAs) are oligonucleotide analogues with the sugar-phosphate backbone replace...
Peptide nucleic acids (PNAs, nucleic acid analogues with a peptide backbone rather than a phosphorib...
Thesis advisor: Abhishek ChatterjeeAbstract Unnatural amino acid (UAA) incorporation is a powerful ...
Peptide nucleic acids (PNAs) were used as encoding tags to enable the analysis of peptide libraries...
Proteomics has made major progress in recent years after the sequencing of the genomes of a substant...
Peptide nucleic acids (PNAs) are oligonucleotide analogues in which the sugar-phosphate backbone has...
This book compiles four review articles and four research papers that highlight recent developments ...
Synthetic molecules that can bind with high sequence specificity to a chosen target in a gene sequen...
Quinone methides (QMs) are electrophilic intermediates that can be generated in vivo to alkylate DNA...
A peptide nucleic acid (PNA) encoded 1296 member peptide library was synthesised and incubated with...
A PNA molecule is a DNA strand where the sugar-phosphate backbone has been replaced by a structurall...
Peptide nucleic acids (PNAs) are DNA analogs in which the normal phosphodiester backbone is replaced...
Protein kinases represent one of the largest families of enzymes. Due to their crucial roles in man...
Biological systems are governed by molecular interactions. At the core of all biological systems is ...
Peptide nucleic acid (PNA) is arguably one of the most successful DNA mimics, despite a most dramati...
Peptide nucleic acids (PNAs) are oligonucleotide analogues with the sugar-phosphate backbone replace...
Peptide nucleic acids (PNAs, nucleic acid analogues with a peptide backbone rather than a phosphorib...
Thesis advisor: Abhishek ChatterjeeAbstract Unnatural amino acid (UAA) incorporation is a powerful ...
Peptide nucleic acids (PNAs) were used as encoding tags to enable the analysis of peptide libraries...
Proteomics has made major progress in recent years after the sequencing of the genomes of a substant...
Peptide nucleic acids (PNAs) are oligonucleotide analogues in which the sugar-phosphate backbone has...
This book compiles four review articles and four research papers that highlight recent developments ...
Synthetic molecules that can bind with high sequence specificity to a chosen target in a gene sequen...
Quinone methides (QMs) are electrophilic intermediates that can be generated in vivo to alkylate DNA...
A peptide nucleic acid (PNA) encoded 1296 member peptide library was synthesised and incubated with...
A PNA molecule is a DNA strand where the sugar-phosphate backbone has been replaced by a structurall...
Peptide nucleic acids (PNAs) are DNA analogs in which the normal phosphodiester backbone is replaced...
Protein kinases represent one of the largest families of enzymes. Due to their crucial roles in man...
Biological systems are governed by molecular interactions. At the core of all biological systems is ...
Peptide nucleic acid (PNA) is arguably one of the most successful DNA mimics, despite a most dramati...
Peptide nucleic acids (PNAs) are oligonucleotide analogues with the sugar-phosphate backbone replace...
Peptide nucleic acids (PNAs, nucleic acid analogues with a peptide backbone rather than a phosphorib...
Thesis advisor: Abhishek ChatterjeeAbstract Unnatural amino acid (UAA) incorporation is a powerful ...