The introduction of autonomous vehicles (AV) will represent a milestone in the evolution of transportation and personal mobility. AVs are expected to significantly reduce accidents and congestion, while being economically and environmentally beneficial. However, many challenges must be overcome before reaching this ideal scenario. This study, which results from on-site visits to top research centres and a comprehensive literature review, provides an overall state-of-the-practice on the subject and identifies critical issues to succeed. For example, although most of the required technology is already available, ensuring the robustness of AVs under all boundary conditions is still a challenge. Additionally, the implementation of AVs must cont...