A novel quantitative model of a guinea-pig ventricular myocyte has been designed with transverse-axial tubular system (TATS) included. This model displays long-term stability and closely reproduces experimental activity-related changes in action potentials and ionic concentrations inside the cell and in the lumen of the TATS. It allows exploration of species-specific functional consequences of the presence of the TATS in a biophysically realistic way
<p>Estimated parameters from the four isolated myocytes (colored circles; bars give standard deviati...
Heterogeneity of myocardium proved to be important for understanding heart physiology and pathophysi...
Background: The cardiomyocyte cell membrane is composed of the surface membrane and a complex system...
International audienceA model of the guinea-pig cardiac ventricular myocyte has been developed that ...
The transverse-axial tubular system (TAT-system) of cardiac muscle is a structure that allows rapid ...
A mathematical model of human ventricular cell incorporating the transverse axial tubular system (TA...
International audienceThe transverse-axial tubular system (TATS) of cardiac ventricular myocytes is ...
In this work, we explored the extent of ion concentration changes in the transverse-axial tubular sy...
Experimental data related to the tubular system of guinea pig and rat ventricular cell were summariz...
In this work, we present a new version of cardiac ventricular cell model incorporating the transvers...
In this work, we explored quantitatively the effect of ion concentration changes in the restricted s...
We present a design of a model of rat ventricular cardiomyocyte with transverse-axial tubular system...
The local control theory of excitation-contraction (EC) coupling asserts that regulation of calcium ...
The transverse tubular system (T-system) of cardiac muscle is a structure that allows rapid propagat...
The paper presents a new description of intracellular Ca2+ dynamics in the model of rat ventricular ...
<p>Estimated parameters from the four isolated myocytes (colored circles; bars give standard deviati...
Heterogeneity of myocardium proved to be important for understanding heart physiology and pathophysi...
Background: The cardiomyocyte cell membrane is composed of the surface membrane and a complex system...
International audienceA model of the guinea-pig cardiac ventricular myocyte has been developed that ...
The transverse-axial tubular system (TAT-system) of cardiac muscle is a structure that allows rapid ...
A mathematical model of human ventricular cell incorporating the transverse axial tubular system (TA...
International audienceThe transverse-axial tubular system (TATS) of cardiac ventricular myocytes is ...
In this work, we explored the extent of ion concentration changes in the transverse-axial tubular sy...
Experimental data related to the tubular system of guinea pig and rat ventricular cell were summariz...
In this work, we present a new version of cardiac ventricular cell model incorporating the transvers...
In this work, we explored quantitatively the effect of ion concentration changes in the restricted s...
We present a design of a model of rat ventricular cardiomyocyte with transverse-axial tubular system...
The local control theory of excitation-contraction (EC) coupling asserts that regulation of calcium ...
The transverse tubular system (T-system) of cardiac muscle is a structure that allows rapid propagat...
The paper presents a new description of intracellular Ca2+ dynamics in the model of rat ventricular ...
<p>Estimated parameters from the four isolated myocytes (colored circles; bars give standard deviati...
Heterogeneity of myocardium proved to be important for understanding heart physiology and pathophysi...
Background: The cardiomyocyte cell membrane is composed of the surface membrane and a complex system...