Computer modelling of effect of transversal tubules on excitation - contraction coupling in cardiac cells (Basic study)

The transverse tubular system (T-system) of cardiac muscle is a structure that allows rapid propagation of excitation into the cell interior. As suggested in many resent experimental works it could have a significant effect on cardiac cell function in **ed by the accumulation or the depletion of ions in restricted tubular space. The aim of our work was to design a mathematical model of electrical activity of cardiac cell including a quantitative description of T-system function and to explore the ph