Constitutive modelling of human perivascular adipose tissue

The mechanical properties of adipose tissue are studied rarely despite the fact that surrounding tissue plays an important role in arterial physiology and mechanobiology. This study deals with the determination of material parameters of human perivascular adipose tissue surrounding the abdominal aorta. The selected representative experimental curve from uniaxial tensile test was used to be fitted by Ogden, Gent, and Fung hyperelastic models assuming isotropic and incompressible material of perivascular tissue. The estimated material parameters are μ = 0.001 MPa and α = 28, μ = 0.026 MPa and Jm =0.067, μ = 0.018 MPa and b = 31.834, respectively. It was concluded that all applied mathematical models predicted nonlinear stress-strain relation ship satisfactorily with coefficient of determination 0.995, 0.981, 0.994, respectively