Nuclear speckles (speckles), enriched in splicing factors, form a distict nuclear compartment within the interchromatin space. It has been schown to serve vicinal active genes as a reservoir of splicing factors.We show that (pre-)spliceosomal assemblyy on pre-mRNA is associated with the speckles in HeLa cells
Chromatin structure is an important factor in the functional coupling between transcription and mRNA...
Chromatin structure is an important factor in the functional coupling between transcription and mRNA...
SC-35 is a non-snRNP spliceosome component that is specifically recognized by the anti-spliceosome m...
Splicing is an essential step in the processing of intron-containing pre-mRNAs prior to their transp...
Speckles are subnuclear structures that are enriched in pre-messenger RNA splicing factors and are l...
Nuclear speckles, also known as interchromatin granule clusters, are nuclear domains enriched in pre...
Speckles are subnuclear structures that are enriched in pre-messenger RNA splicing factors and are l...
Pre-mRNA splicing is a predominantly co-transcriptional event which involves a large number of essen...
In actively transcribing cells, factors involved in pre-mRNA splicing localize in a speckled pattern...
Direct localization of specific genes, RNAs, and proteins has allowed the dissection of individual n...
Recent studies have suggested that small nuclear ribonucleoprotein particles (snRNPs), non-snRNP spl...
Chromatin structure is an important factor in the functional coupling between transcription and mRNA...
Chromatin structure is an important factor in the functional coupling between transcription and mRNA...
SC-35 is a non-snRNP spliceosome component that is specifically recognized by the anti-spliceosome m...
Splicing is an essential step in the processing of intron-containing pre-mRNAs prior to their transp...
Speckles are subnuclear structures that are enriched in pre-messenger RNA splicing factors and are l...
Nuclear speckles, also known as interchromatin granule clusters, are nuclear domains enriched in pre...
Speckles are subnuclear structures that are enriched in pre-messenger RNA splicing factors and are l...
Pre-mRNA splicing is a predominantly co-transcriptional event which involves a large number of essen...
In actively transcribing cells, factors involved in pre-mRNA splicing localize in a speckled pattern...
Direct localization of specific genes, RNAs, and proteins has allowed the dissection of individual n...
Recent studies have suggested that small nuclear ribonucleoprotein particles (snRNPs), non-snRNP spl...
Chromatin structure is an important factor in the functional coupling between transcription and mRNA...
Chromatin structure is an important factor in the functional coupling between transcription and mRNA...
SC-35 is a non-snRNP spliceosome component that is specifically recognized by the anti-spliceosome m...