Metabolic fluxes in pathways of biosynthesis of branched-chain amino acids can be modulated by different changes in expression of genes of the desired pathway as well as those of competing pathways. Site-directed mutagenesis of promoters of the respective genes is a suitable tool to obtain desired changes in gene expression
Lubitz DJ. Metabolic engineering of Corynebacterium glutamicum for production of L-glutamate and oth...
Irla M. Transcriptome- and genome-based metabolic engineering of Bacillus methanolicus for productio...
Mutants of Corynebacterium glutamicum were made and enzymatically characterized to clone ilvD and il...
Biosynthesis pathways of branched-chain amino acids (valine, leucine, isoleucine) are controlled by ...
Promoters of genes involved in biosynthesis of branched-chain amino acids in Corynebacterium glutami...
L-valine is an essential amino acid with a great medical and industoial importance and the need for ...
Single gene overexpression in product pathways such as lysine synthesis has often been employed in m...
Kalinowski J. Regulatory and Metabolic Networks for Amino Acid Production by Corynebacterium glutami...
Mindt M. Access to N-alkylated amino acids by metabolic engineering of Corynebacterium glutamicum an...
McHardy AC, Tauch A, Rückert C, Pühler A, Kalinowski J. Genome-based analysis of biosynthetic aminot...
<i>Corynebacterium glutamicum</i> is an important organism for the industrial production of amino ac...
Dedicated to Prof. Dr. Dietmar Hempel on the occasion of his 65th birthday Abstract The Gram-positiv...
<p>(A) Orthogonal metabolic output in a bacterial cell is depicted as a function (<i>f</i>) of the g...
Wendisch VF, ed. Amino Acid Biosynthesis – Pathways, Regulation and Metabolic Engineering. Microbiol...
Haupka C. Metabolic engineering of methylotrophic Bacillus methanolicus and non-methylotrophic Cory...
Lubitz DJ. Metabolic engineering of Corynebacterium glutamicum for production of L-glutamate and oth...
Irla M. Transcriptome- and genome-based metabolic engineering of Bacillus methanolicus for productio...
Mutants of Corynebacterium glutamicum were made and enzymatically characterized to clone ilvD and il...
Biosynthesis pathways of branched-chain amino acids (valine, leucine, isoleucine) are controlled by ...
Promoters of genes involved in biosynthesis of branched-chain amino acids in Corynebacterium glutami...
L-valine is an essential amino acid with a great medical and industoial importance and the need for ...
Single gene overexpression in product pathways such as lysine synthesis has often been employed in m...
Kalinowski J. Regulatory and Metabolic Networks for Amino Acid Production by Corynebacterium glutami...
Mindt M. Access to N-alkylated amino acids by metabolic engineering of Corynebacterium glutamicum an...
McHardy AC, Tauch A, Rückert C, Pühler A, Kalinowski J. Genome-based analysis of biosynthetic aminot...
<i>Corynebacterium glutamicum</i> is an important organism for the industrial production of amino ac...
Dedicated to Prof. Dr. Dietmar Hempel on the occasion of his 65th birthday Abstract The Gram-positiv...
<p>(A) Orthogonal metabolic output in a bacterial cell is depicted as a function (<i>f</i>) of the g...
Wendisch VF, ed. Amino Acid Biosynthesis – Pathways, Regulation and Metabolic Engineering. Microbiol...
Haupka C. Metabolic engineering of methylotrophic Bacillus methanolicus and non-methylotrophic Cory...
Lubitz DJ. Metabolic engineering of Corynebacterium glutamicum for production of L-glutamate and oth...
Irla M. Transcriptome- and genome-based metabolic engineering of Bacillus methanolicus for productio...
Mutants of Corynebacterium glutamicum were made and enzymatically characterized to clone ilvD and il...