Experimental data related to the tubular system of guinea pig and rat ventricular cell were summarized and incorporated into quantitative models of cellular activity. The results of simulations suggest that activity-dependent depletion of Ca2+ within the t-tubule lumen lowers the intracellular Ca load, intracellular Ca2+ transients and hence the inotropic status of ventricular myocytes
Intracellular Ca2+ load and Ca2+ transient are considerably dependent on distribution of sarcolemmal...
AbstractThe action potential of cardiac ventricular myocytes is characterized by its long duration, ...
The transverse (t-) tubules of cardiac ventricular myocytes are invaginations of the surface membran...
We present a design of a model of rat ventricular cardiomyocyte with transverse-axial tubular system...
The paper presents a new description of intracellular Ca2+ dynamics in the model of rat ventricular ...
International audienceA model of the guinea-pig cardiac ventricular myocyte has been developed that ...
The paper presents a new description of intracellular Ca2+ dynamics in the model of rat ventricular ...
In this work, we explored the extent of ion concentration changes in the transverse-axial tubular sy...
The transverse-axial tubular system (TAT-system) of cardiac muscle is a structure that allows rapid ...
A novel quantitative model of a guinea-pig ventricular myocyte has been designed with transverse-axi...
The t-tubules of mammalian ventricular myocytes are invaginations of the cell membrane that occur at...
A mathematical model of human ventricular cell incorporating the transverse axial tubular system (TA...
In this work, we present a new version of cardiac ventricular cell model incorporating the transvers...
The transverse tubular system of rabbit ventricular myocytes consists of cell membrane invaginations...
AbstractWe have developed a detailed mathematical model for Ca2+ handling and ionic currents in the ...
Intracellular Ca2+ load and Ca2+ transient are considerably dependent on distribution of sarcolemmal...
AbstractThe action potential of cardiac ventricular myocytes is characterized by its long duration, ...
The transverse (t-) tubules of cardiac ventricular myocytes are invaginations of the surface membran...
We present a design of a model of rat ventricular cardiomyocyte with transverse-axial tubular system...
The paper presents a new description of intracellular Ca2+ dynamics in the model of rat ventricular ...
International audienceA model of the guinea-pig cardiac ventricular myocyte has been developed that ...
The paper presents a new description of intracellular Ca2+ dynamics in the model of rat ventricular ...
In this work, we explored the extent of ion concentration changes in the transverse-axial tubular sy...
The transverse-axial tubular system (TAT-system) of cardiac muscle is a structure that allows rapid ...
A novel quantitative model of a guinea-pig ventricular myocyte has been designed with transverse-axi...
The t-tubules of mammalian ventricular myocytes are invaginations of the cell membrane that occur at...
A mathematical model of human ventricular cell incorporating the transverse axial tubular system (TA...
In this work, we present a new version of cardiac ventricular cell model incorporating the transvers...
The transverse tubular system of rabbit ventricular myocytes consists of cell membrane invaginations...
AbstractWe have developed a detailed mathematical model for Ca2+ handling and ionic currents in the ...
Intracellular Ca2+ load and Ca2+ transient are considerably dependent on distribution of sarcolemmal...
AbstractThe action potential of cardiac ventricular myocytes is characterized by its long duration, ...
The transverse (t-) tubules of cardiac ventricular myocytes are invaginations of the surface membran...