CTL (Cytotoxic T. Lymphocytes) destroy virally infected cells and tumor cells via the secretion of lytic molecules stored in intracellular granules. They are key components of the anti-cancer immune response and it is therefore crucial to study in depth, and possibly enhance, their biological responses against tumors. In [CMR+15], we introduced a stochastic dynamical model that involves interacting particles based on experimentally measured parameters. It therefore makes it possible to describe CTL function during immuno-editing. At the same time, we showed on simulations that a bias in CTL motility inducing a progressive attraction towards a few scout CTL, which have detected the nodule, enhances early productive collisions and drastically...
<p>(<i>A</i>) Evolution of the probability of the nodule eradication (<i>P</i><sub><i>S</i></sub>) w...
Spatial interactions between cancer and immune cells, as well as the recognition of tumour antigens ...
International audienceUnderstanding the human cytotoxic T lymphocyte (CTL) biology is crucial to dev...
CTL (Cytotoxic T. Lymphocytes) destroy virally infected cells and tumor cells via the secretion of l...
The dynamics of the interaction between Cytotoxic T Lymphocytes (CTL) and tumor cells has been addre...
The dynamics of the interaction between Cytotoxic T Lymphocytes (CTL) and tumor cells has been addre...
<div><p>The dynamics of the interaction between Cytotoxic T Lymphocytes (CTL) and tumor cells has be...
This thesis studies some statistical and probability properties of the dynamic of Cytotoxic T Lympho...
The dynamics of the interaction between Cytotoxic T Lymphocytes (CTL) and tumor cells has been addre...
Experimental results on the immune response to cancer indicate that activation of cytotoxic T lympho...
The competition between cancer cells and immune system cells in inhomogeneous conditions is describe...
This work deals with the modeling of interactions between immune system cells and cancer cells, whic...
Abstract Background In this work a mathematical model describing the growth of a solid tumour in the...
Chimeric antigen receptor (CAR) T cell therapy is a remarkably effective immunotherapy that relies o...
F. R. Macfarlane funded by the Engineering and Physical Sciences Research Council (EPSRC).A growing ...
<p>(<i>A</i>) Evolution of the probability of the nodule eradication (<i>P</i><sub><i>S</i></sub>) w...
Spatial interactions between cancer and immune cells, as well as the recognition of tumour antigens ...
International audienceUnderstanding the human cytotoxic T lymphocyte (CTL) biology is crucial to dev...
CTL (Cytotoxic T. Lymphocytes) destroy virally infected cells and tumor cells via the secretion of l...
The dynamics of the interaction between Cytotoxic T Lymphocytes (CTL) and tumor cells has been addre...
The dynamics of the interaction between Cytotoxic T Lymphocytes (CTL) and tumor cells has been addre...
<div><p>The dynamics of the interaction between Cytotoxic T Lymphocytes (CTL) and tumor cells has be...
This thesis studies some statistical and probability properties of the dynamic of Cytotoxic T Lympho...
The dynamics of the interaction between Cytotoxic T Lymphocytes (CTL) and tumor cells has been addre...
Experimental results on the immune response to cancer indicate that activation of cytotoxic T lympho...
The competition between cancer cells and immune system cells in inhomogeneous conditions is describe...
This work deals with the modeling of interactions between immune system cells and cancer cells, whic...
Abstract Background In this work a mathematical model describing the growth of a solid tumour in the...
Chimeric antigen receptor (CAR) T cell therapy is a remarkably effective immunotherapy that relies o...
F. R. Macfarlane funded by the Engineering and Physical Sciences Research Council (EPSRC).A growing ...
<p>(<i>A</i>) Evolution of the probability of the nodule eradication (<i>P</i><sub><i>S</i></sub>) w...
Spatial interactions between cancer and immune cells, as well as the recognition of tumour antigens ...
International audienceUnderstanding the human cytotoxic T lymphocyte (CTL) biology is crucial to dev...