Antifungal activity of the essential oil of Valeriana officinalis L.

In this paper essential oil of V. officinalis as potential antifungal agent was analyzed. Following micromycetes as test organisms were included: Penicillium ochrochloron, Alternaria alternata, Aureobasidium pullulans, Trichoderma viride, Cladosporium cladosporioides, Fulvia fulvium, Phomopsis helianthi and dermatomicetes Trichophyton rubrum, Trichophyton tonsurans, Epidermophyton floccosum i Microsporum canis. Throughout the macrodilution method on agar substrates, after incubation period, minimum inhibition concentration (MIC) was recorded. The concentration of 20 ml/ml showed fungistatic activity against T. viride. For species P. ochrochloron, A. alternata, A. pullulans MIC was 10 ml/ml, and for C. cladosporioides, F. fulvium and P. helianthi like for analyzed dermatomycetes MIC was 5 ml/ml. Further investigations will comprise larger number of testing fungi and examination of antifungal activities of single essential oil components of V. officinalis.U ovom radu analizirano je etarsko ulje V. officinalis L. kao potencijalni antifungalni agens. Kao test organizmi korišćene su sledeće mikromicete: Penicillium ochrochloron, Alternaria alternata, Aureobasidium pullulans, Trichoderma viride, Cladosporium cladosporioides, Fulvia fulvium, Phomopsis helianthi i dermatomicete Trichophyton rubrum, Trichophyton tonsurans, Epidermophyton floccosum i Microsporum canis. Makrodilucionom metodom su na agarnim podlogama utvrđivane minimalne inhibitorne koncentracije (MIC). Koncentracija od 20 ml/ml pokazala je fungistatsku aktivnost na vrstu T. viride. Za vrste P. ochrochloron, A. alternata, A. pullulans MIC je 10 ml/ml, a za C. cladosporioides, F. fulvium i P. helianthi kao i za analizirane dermatomicete MIC iznosi 5ml/ml. Dalja istraživanja obuhvatiće veći broj testiranih gljiva i ispitivanje antifungalne aktivnosti pojedinačnih komponenti etarskog ulja V. officinalis.nul