Topics
BelgradePlace
ArxFood
ablationCompany
diabetesDisease
DNA methyltransferaseBiomolecule
insulinProtein
regenerative medicineOrganisation
transcription factorProtein
SerbiaPlace
Since diabetes is characterized by impaired ability of pancreatic beta-cells to respond and/or produce insulin, new approaches for renewal and replacement of deficient beta-cells are indispensable. Generation of new insulin-producing cells from other cell types is a major aim of regenerative medicine. It has been shown that loss of the master regulatory transcription factor Arx is sufficient to induce the conversion of alpha cells to functional insulin-producing cells. Previous experiments revealed dedifferentiation of pancreatic beta to alpha cells in response to ablation of DNA methyltransferase 1 (Dnmt1) in beta cells.Poster session presented at: CoMBoS. 1st Congress of Molecular Biologists of Serbia; 2017 Sep 20-22; Belgrade, Serbia. (P...
Expansion of beta cells from the limited number of adult human islet donors is an attractive prospec...
Maturity-onset diabetes of the young type 1 (MODY1) is a form of monogenic diabetes caused by single...
Expansion of beta cells from the limited number of adult human islet donors is an attractive prospec...
Since diabetes is characterized by impaired ability of pancreatic beta-cells to respond and/or produ...
Introduction: Since diabetes is characterized by impaired ability of pancreatic betacells to respond...
Introduction: Beta cell dysfunction by loss of beta cell identity, dedifferentiation, and the presen...
Introduction: Beta cell dysfunction by loss of beta cell identity, dedifferentiation, and the presen...
Introduction: Beta cell dysfunction by loss of beta cell identity, dedifferentiation, and the presen...
Diabetes mellitus (DM) is a severe and frequent disease with increasing prevalence. It is not possib...
<div><p>The onset of metabolic dysregulation in type 1 diabetes (T1D) occurs after autoimmune destru...
An important aim of Type I diabetes therapeutic strategies is the replenishment of functional beta c...
Both type 1 and type 2 diabetes are conditions that are associated with the loss of insulin-producin...
Both type 1 and type 2 diabetes are conditions that are associated with the loss of insulin-producin...
Diabetes mellitus results in elevated blood glucose levels due to an insufficiency of the glucose lo...
The onset of metabolic dysregulation in type 1 diabetes (T1D) occurs after autoimmune destruction of...
Expansion of beta cells from the limited number of adult human islet donors is an attractive prospec...
Maturity-onset diabetes of the young type 1 (MODY1) is a form of monogenic diabetes caused by single...
Expansion of beta cells from the limited number of adult human islet donors is an attractive prospec...
Since diabetes is characterized by impaired ability of pancreatic beta-cells to respond and/or produ...
Introduction: Since diabetes is characterized by impaired ability of pancreatic betacells to respond...
Introduction: Beta cell dysfunction by loss of beta cell identity, dedifferentiation, and the presen...
Introduction: Beta cell dysfunction by loss of beta cell identity, dedifferentiation, and the presen...
Introduction: Beta cell dysfunction by loss of beta cell identity, dedifferentiation, and the presen...
Diabetes mellitus (DM) is a severe and frequent disease with increasing prevalence. It is not possib...
<div><p>The onset of metabolic dysregulation in type 1 diabetes (T1D) occurs after autoimmune destru...
An important aim of Type I diabetes therapeutic strategies is the replenishment of functional beta c...
Both type 1 and type 2 diabetes are conditions that are associated with the loss of insulin-producin...
Both type 1 and type 2 diabetes are conditions that are associated with the loss of insulin-producin...
Diabetes mellitus results in elevated blood glucose levels due to an insufficiency of the glucose lo...
The onset of metabolic dysregulation in type 1 diabetes (T1D) occurs after autoimmune destruction of...
Expansion of beta cells from the limited number of adult human islet donors is an attractive prospec...
Maturity-onset diabetes of the young type 1 (MODY1) is a form of monogenic diabetes caused by single...
Expansion of beta cells from the limited number of adult human islet donors is an attractive prospec...
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