Polycomb proteins are well-known epigenetic repressors with unexplained roles in chromatin folding. In this issue of Molecular Cell, Kundu et al. (2017) investigate the structures of PRC1-mediated domains in stem cells and probe their changes upon differentiation and in PRC knockouts
Establishment and maintenance of transcriptional identity is the cornerstone of tissue organization ...
A cell uses epigenetic regulation mechanisms to activate or deactivate genetic characteristics, i.e....
Several noncanonical type-1 Polycomb Repressive Complexes (PRC1) that act independently of PRC2 have...
Development of complex multicellular organisms depends on precise spatiotemporal regulation of trans...
In embryonic stem (ES) cells, bivalent chromatin domains with overlapping repressive (H3 lysine 27 t...
Precise spatio-temporal regulation of gene expression is required for development of multicellular o...
SummaryChromatin modifying activities inherent to polycomb repressive complexes PRC1 and PRC2 play a...
Polycomb group (PcG) proteins function as chromatin-based transcriptional repressors that are essen...
Polycomb group proteins (PcGs) generate chromatin-modifying complexes that regulate gene expression....
Chromatin modifying activities inherent to polycomb repressive complexes PRC1 and PRC2 play an ess...
The Polycomb repressive system is an essential chromatin-based regulator of gene expression. Despite...
Polycomb group (PcG) proteins play critical roles in the epigenetic inheritance of cell fate. The Po...
The multi-subunit Polycomb Repressive Complex (PRC) 1 and 2 act, either independently or synergistic...
SummaryThe mechanisms by which the major Polycomb group (PcG) complexes PRC1 and PRC2 are recruited ...
In embryonic stem (ES) cells, bivalent chromatin domains with overlapping repressive (H3 lysine 27 t...
Establishment and maintenance of transcriptional identity is the cornerstone of tissue organization ...
A cell uses epigenetic regulation mechanisms to activate or deactivate genetic characteristics, i.e....
Several noncanonical type-1 Polycomb Repressive Complexes (PRC1) that act independently of PRC2 have...
Development of complex multicellular organisms depends on precise spatiotemporal regulation of trans...
In embryonic stem (ES) cells, bivalent chromatin domains with overlapping repressive (H3 lysine 27 t...
Precise spatio-temporal regulation of gene expression is required for development of multicellular o...
SummaryChromatin modifying activities inherent to polycomb repressive complexes PRC1 and PRC2 play a...
Polycomb group (PcG) proteins function as chromatin-based transcriptional repressors that are essen...
Polycomb group proteins (PcGs) generate chromatin-modifying complexes that regulate gene expression....
Chromatin modifying activities inherent to polycomb repressive complexes PRC1 and PRC2 play an ess...
The Polycomb repressive system is an essential chromatin-based regulator of gene expression. Despite...
Polycomb group (PcG) proteins play critical roles in the epigenetic inheritance of cell fate. The Po...
The multi-subunit Polycomb Repressive Complex (PRC) 1 and 2 act, either independently or synergistic...
SummaryThe mechanisms by which the major Polycomb group (PcG) complexes PRC1 and PRC2 are recruited ...
In embryonic stem (ES) cells, bivalent chromatin domains with overlapping repressive (H3 lysine 27 t...
Establishment and maintenance of transcriptional identity is the cornerstone of tissue organization ...
A cell uses epigenetic regulation mechanisms to activate or deactivate genetic characteristics, i.e....
Several noncanonical type-1 Polycomb Repressive Complexes (PRC1) that act independently of PRC2 have...
DOI
Add to ORKG