A broad variety of normal human tissues were examined for the expression of Thomsen-Friedenreich (TF)-related histo-blood group antigens, TF (Gal beta 1-3GalNAc alpha 1-R), Tn (TF precursor, GalNAc alpha 1-R), sialosyl-Tn (NeuAc alpha 2-6GalNAc alpha 1-R), considered to be useful in cancer diagnosis and immunotherapy, and sialosyl-TF, the cryptic form of TF. These antigens or, more correctly, glycotopes, were determined by immunohistochemistry with at least two monoclonal antibodies (mAbs) each (except sialosyl-TF) as well as by lectin histochemistry. For a better dissection of sialosyl-TF and TF glycotopes, tissue sections were pretreated with galactose oxidase or the galactose oxidase-Schiff sequence. Staining with mAbs appeared to be mor...
Alterations in the glycosylation of serum total immunoglobulins show these antibodies to have a diag...
Aim. To study whether alterations in the sialylation of antibodies (Ab) specific to the Thomsen-Frie...
Poly-N-acetyllactosaminyl structures are considered to be patho- physiologically important carbohyd...
The Thomsen-Friedenreich (TF) disaccharide, galactose (Gal){beta}1- 3GalNAc{alpha}-, is a blood grou...
Thomsen-Friedenreich antigen (T antigen) has been supposed to be a cancer-specific carbohydrate anti...
Thomsen-Friedenreich (TF)-related blood group antigens, such as TF, Tn, and their sialylated variant...
On the basis of their known fine specificities we evaluated the immunohistochemical marker qualities...
The Thomsen-Friedenreich (TF or T) antigen, Galβ1-3GalNAcα1-O-Ser/Thr, is the core 1 structure of O-...
The Thomsen-Friedenreich (TF) antigen is expressed in a majority of human tumors due to aberrant gly...
The simple mucin-type carbohydrate antigens Tn, sialosyl-Tn, T and the 'cryptic' sialylated variant ...
Simple mucin-type carbohydrate antigens, T, Tn, and sialosysl-Tn, have been found to be good markers...
Recently, several investigators have demonstrated that Thomsen-Friedenreich antigen (T-Ag) and Tn-an...
The Thomsen-Friedenreich-antigen, Gal(β1–3)GalNAc(α1-O-Ser/Thr (TF-antigen), is presented on the sur...
Immunohistochemical analysis of the expression of simple mucin-type carbohydrate antigens (Tn, sialy...
International audienceThe Thomsen Friedenreich (TF) carbohydrate antigens are a group of short O-gly...
Alterations in the glycosylation of serum total immunoglobulins show these antibodies to have a diag...
Aim. To study whether alterations in the sialylation of antibodies (Ab) specific to the Thomsen-Frie...
Poly-N-acetyllactosaminyl structures are considered to be patho- physiologically important carbohyd...
The Thomsen-Friedenreich (TF) disaccharide, galactose (Gal){beta}1- 3GalNAc{alpha}-, is a blood grou...
Thomsen-Friedenreich antigen (T antigen) has been supposed to be a cancer-specific carbohydrate anti...
Thomsen-Friedenreich (TF)-related blood group antigens, such as TF, Tn, and their sialylated variant...
On the basis of their known fine specificities we evaluated the immunohistochemical marker qualities...
The Thomsen-Friedenreich (TF or T) antigen, Galβ1-3GalNAcα1-O-Ser/Thr, is the core 1 structure of O-...
The Thomsen-Friedenreich (TF) antigen is expressed in a majority of human tumors due to aberrant gly...
The simple mucin-type carbohydrate antigens Tn, sialosyl-Tn, T and the 'cryptic' sialylated variant ...
Simple mucin-type carbohydrate antigens, T, Tn, and sialosysl-Tn, have been found to be good markers...
Recently, several investigators have demonstrated that Thomsen-Friedenreich antigen (T-Ag) and Tn-an...
The Thomsen-Friedenreich-antigen, Gal(β1–3)GalNAc(α1-O-Ser/Thr (TF-antigen), is presented on the sur...
Immunohistochemical analysis of the expression of simple mucin-type carbohydrate antigens (Tn, sialy...
International audienceThe Thomsen Friedenreich (TF) carbohydrate antigens are a group of short O-gly...
Alterations in the glycosylation of serum total immunoglobulins show these antibodies to have a diag...
Aim. To study whether alterations in the sialylation of antibodies (Ab) specific to the Thomsen-Frie...
Poly-N-acetyllactosaminyl structures are considered to be patho- physiologically important carbohyd...