Influence of cardiovascular related disease on periodontitis

Objcetives: The aim of this study was to evaluate the influence of cardiovascular related diseas(CVD-R) on periodontitis. Methods: The nested case-control study was performed among 550 male workess, who submitted written consent, out or 2002 Workes' Health Cohort(N=1,800). CVD-R such as metabolic syndrome(MS), hypertension, body mass index(BMI). low HCL-cholesterol(HDL-C), fasting blood sugar(FBS) were evaluated in 2002 and periodontitis(probing pocket depth>4mm) was determined in 2004. Age, education, monthly income, parental medical history, smokingm drinkin, physical excerise and past periodontal status were used as confounders. For obtaining odd ratos(OR). bivariate and multivariate logistic regression analysis were applied. Results: MS increased periodontitis, which was not statisically significant (p=0.495). Hypertension might increase periocontitis(p=0.056), showed OR or 1.4(95% Confidence Interval(CI)=0.90-2.29)adjusted for age, education, monthly income and past periodontal status, parental medical history, smoking, drinking and physicl excercise. Conclusions: Hypertension showed a possibility to increase periodontitis. CVD-R such as MS, hypertension, BMI, HDL-C, FBS were not associated with periodontitis.서울대학교 발전기구 신임교수연구비(850-20030095