In this study, the effect of shape and morphology of dry particles for inhalation is investigated. The optimum design of micro-particle for better delivery performance is determined. Preliminarily, different shape macro-particles with low sphericity are experimented in a confined medium to determine the impact of shape irregularities on wall effect during gravitational settling. Then different shape micro-particles including spherical, pollen, plate, cube, and needle shape particles are synthesized with a similar aerodynamic size range of <5μm. Flowability and in vitro dispersion and deposition experimentation using cascade impactor are performed with the different shape particles. Particles with shape that have preferable behavior are form...
The atmospheric particles from different sources, and the therapeutic particles from various drug de...
The pulmonary drug delivery system offers several merits over other drug delivery systems and theref...
In vitro study of the deposition of drug particles is commonly used during development of formulatio...
In this study, the effect of shape and morphology of dry particles for inhalation is investigated. T...
Abstract. The shape effects of dry particles on flowability, aerosolization, and deposition properti...
Pulmonary drug delivery has become an attractive route of drug administration to the human body for ...
The performance of a pharmaceutical powder aerosol is mainly dependent on aerosol physicochemical pr...
Dry powder inhalation (DPI) formulations have been playing a critical part to increase the effective...
Drug delivery via the pulmonary route has increasingly received much attention in recent years. Inha...
Background: The use of non-invasive inhaled aerosols for pulmonary drug delivery continues to grow. ...
textThe influence of the size and morphology of carrier particles on drug dispersion performance fro...
Inhalation of therapeutics has been gaining importance owing to immense advantages offered by pulmon...
Background: A key issue in pulmonary drug delivery is improvement of the delivery device for effecti...
Inhaled medication is standard therapy in asthma and COPD. However the amount of drug reaching the l...
Drug delivery by inhalation has been routinely used for the treatment of localized diseases such as ...
The atmospheric particles from different sources, and the therapeutic particles from various drug de...
The pulmonary drug delivery system offers several merits over other drug delivery systems and theref...
In vitro study of the deposition of drug particles is commonly used during development of formulatio...
In this study, the effect of shape and morphology of dry particles for inhalation is investigated. T...
Abstract. The shape effects of dry particles on flowability, aerosolization, and deposition properti...
Pulmonary drug delivery has become an attractive route of drug administration to the human body for ...
The performance of a pharmaceutical powder aerosol is mainly dependent on aerosol physicochemical pr...
Dry powder inhalation (DPI) formulations have been playing a critical part to increase the effective...
Drug delivery via the pulmonary route has increasingly received much attention in recent years. Inha...
Background: The use of non-invasive inhaled aerosols for pulmonary drug delivery continues to grow. ...
textThe influence of the size and morphology of carrier particles on drug dispersion performance fro...
Inhalation of therapeutics has been gaining importance owing to immense advantages offered by pulmon...
Background: A key issue in pulmonary drug delivery is improvement of the delivery device for effecti...
Inhaled medication is standard therapy in asthma and COPD. However the amount of drug reaching the l...
Drug delivery by inhalation has been routinely used for the treatment of localized diseases such as ...
The atmospheric particles from different sources, and the therapeutic particles from various drug de...
The pulmonary drug delivery system offers several merits over other drug delivery systems and theref...
In vitro study of the deposition of drug particles is commonly used during development of formulatio...