Publications that compare randomized controlled trial and cohort study results on the effects of postmenopausal estrogen-plus-progestin therapy are reviewed. The 2 types of studies agree in identifying an early elevation in coronary heart disease risk, and a later developing elevation in breast cancer risk. Effects among women who begin hormone therapy within a few years after the menopause may be comparatively more favorable for coronary heart disease and less favorable for breast cancer. These analyses illustrate the potential of modern data analysis methods to enhance the reliability and interpretation of epidemiologic data
Objectives Prospective observational studies (OSs) that collect adequate information about confounde...
ContextThe timing of initiation of hormone therapy may influence its effect on cardiovascular diseas...
Menarche and menopause mark the onset and cessation, respectively, of ovarian activity associated wi...
Background Half the epidemiological studies with information about menopausal hormone therapy and ov...
Background The Collaborative Group on Hormonal Factors in Breast Cancer has brought together and rea...
BACKGROUND: The Collaborative Group on Hormonal Factors in Breast Cancer has brought together and re...
Background: Published findings on breast cancer risk associated with different types of menopausal h...
Background: Published findings on breast cancer risk associated with different types of menopausal h...
Hormone replacement therapy (HRT) is used to help women suffering from menopausal symptoms and reduc...
Background Half the epidemiological studies with information about menopausal hormone therapy and ov...
BACKGROUND: Half the epidemiological studies with information about menopausal hormone therapy and o...
Circumstances in which both randomized controlled trial and observational study data are available p...
BACKGROUND: Menarche and menopause mark the onset and cessation, respectively, of ovarian activity a...
The authors further analyzed results from the Women’s Health Initiative randomized trials (1993–2004...
IMPORTANCE: Menopausal hormone therapy continues in clinical use but questions remain regarding its ...
Objectives Prospective observational studies (OSs) that collect adequate information about confounde...
ContextThe timing of initiation of hormone therapy may influence its effect on cardiovascular diseas...
Menarche and menopause mark the onset and cessation, respectively, of ovarian activity associated wi...
Background Half the epidemiological studies with information about menopausal hormone therapy and ov...
Background The Collaborative Group on Hormonal Factors in Breast Cancer has brought together and rea...
BACKGROUND: The Collaborative Group on Hormonal Factors in Breast Cancer has brought together and re...
Background: Published findings on breast cancer risk associated with different types of menopausal h...
Background: Published findings on breast cancer risk associated with different types of menopausal h...
Hormone replacement therapy (HRT) is used to help women suffering from menopausal symptoms and reduc...
Background Half the epidemiological studies with information about menopausal hormone therapy and ov...
BACKGROUND: Half the epidemiological studies with information about menopausal hormone therapy and o...
Circumstances in which both randomized controlled trial and observational study data are available p...
BACKGROUND: Menarche and menopause mark the onset and cessation, respectively, of ovarian activity a...
The authors further analyzed results from the Women’s Health Initiative randomized trials (1993–2004...
IMPORTANCE: Menopausal hormone therapy continues in clinical use but questions remain regarding its ...
Objectives Prospective observational studies (OSs) that collect adequate information about confounde...
ContextThe timing of initiation of hormone therapy may influence its effect on cardiovascular diseas...
Menarche and menopause mark the onset and cessation, respectively, of ovarian activity associated wi...