The role of tumor-associated macro phages in breast cancer

Interaction of Tumor-Associated Macrophages (TAMs) with tumor cells gives insights into tumor progression and into a novel therapeutic strategy. In papillary thyroid cancer, patients with tumors containing TAMs had a better prognosis than patients without TAMs. In prostatic cancer, the reduced of total TAMs can be used as a novel prognostic marker. In melanoma maligna, high number of TAMs was statistically significant associated with poor response to treatment. In breast cancer progression, the role of TAMs is still unclear