3-(4\u27-bromophenyl)-4,6-Dimethoxy-2 Methylindole.

344=Bromopheny1)-4,6-dimethoxy-2-methylindole has been synthesized from 4, 6-dimethoxyaniline via the modified Bischler method. Reaction of 4,6-dimethoxyaniline with 2,4-dibromopropiophenone gave an aniline ketone in 85%, and then it was protected to give the amido ketone as a white solid. Cyclization of amido ketone was performed by trifluoroacetic acid and subsequent deprotection with potassium hydroxide in methanol afforded a white solid of 3(4\u27-bromopheny0-4,6-dimethoxy-2-methylindole in 86%. Keywords: 4, 6-dimethoxyaniline, 2-methylindole, Bischler metho