Facile enantiospecific syntheses of oxabicyclo[4.4.0]decene-diones from carvone via mild Lewis acid mediated lactonizations

362-370An efficient and concise enantiospecific syntheses of oxabicyclo[4.4.0]decene-diones have been accomplished starting from carvone. This strategy is a chiron based approach by making use of mild Lewis acid mediated intramolecular lactonization as key step for the formation of fused bicyclic lactones. Notably, these bicyclic lactones constitute bicyclic carbon framework of diterpene natural products