Add to ORKG550-555QSAR analysis of a series of previously synthesized p-substituted aromatic hydrazones tested for growth inhibitory activity against Bacillus subtilis, was performed using several physicochemical descriptors: Surface tension (ST), Molar Refraction (MR), Molar Volume (MV), Parachor (Pc), Index of Refractivity (η); Density (D) and Polarizability (α). Two-parameter models were obtained and validated by using several statistical parameters: R; R2adj; F-test; Sd; Rped; PRESS/SSY; Q2; SPRESS; PSE and Q. Both the parameters (D and α) contributing to statistically best model (model 16) have positive input to the modeling of biological activity of selected hydrazones
The inevitable consequence of the widespread use of antimicrobial agents has been the emergence of a...
A set of benzimidazole derivatives were tested for their inhibitory activities against the Gram-nega...
Some novel hydrazone derivatives 6a–o were synthesized from the key intermediate 4-Chloro-N-(2-hydra...
One important class of organic compounds is hydrazones which find huge application in many scientifi...
In continuation of our endeavor towards the development of potent and effective antimicrobial agents...
A series of naphthalen-1-yl-acetic acid benzylidene/(1-phenyl-ethylidene)-hydrazides (1-36) was synt...
To assess electronic absorption spectra, molecular docking, and antibacterial activity, 12 new hydra...
Hydrazone derivatives represent one of the most active classes of compounds possessing a broad spect...
Benzenesulfonicacid-1-methylhydrazide (1) and its four aromatic sulfonyl hydrazone derivatives (laid...
The comparative QSAR is a tool for validating any statistical model that seems to be reasonable in d...
A series of isonicotinic acid hydrazide derivatives (1-19) was synthesized and tested in vitro for a...
The enhancement of bacterial resistance of pathogens to currently available antibiotics constitutes ...
Despite the adverse effects of microbial hazards on public health, major pharmaceutical firms have l...
A series of benzylidene hydrazides (1-20) was synthesized and tested, in vitro, for antibacterial, a...
ABSTRACT: In the present work, efforts have been made to model the antibacterial activity of 4-thiaz...
The inevitable consequence of the widespread use of antimicrobial agents has been the emergence of a...
A set of benzimidazole derivatives were tested for their inhibitory activities against the Gram-nega...
Some novel hydrazone derivatives 6a–o were synthesized from the key intermediate 4-Chloro-N-(2-hydra...
One important class of organic compounds is hydrazones which find huge application in many scientifi...
In continuation of our endeavor towards the development of potent and effective antimicrobial agents...
A series of naphthalen-1-yl-acetic acid benzylidene/(1-phenyl-ethylidene)-hydrazides (1-36) was synt...
To assess electronic absorption spectra, molecular docking, and antibacterial activity, 12 new hydra...
Hydrazone derivatives represent one of the most active classes of compounds possessing a broad spect...
Benzenesulfonicacid-1-methylhydrazide (1) and its four aromatic sulfonyl hydrazone derivatives (laid...
The comparative QSAR is a tool for validating any statistical model that seems to be reasonable in d...
A series of isonicotinic acid hydrazide derivatives (1-19) was synthesized and tested in vitro for a...
The enhancement of bacterial resistance of pathogens to currently available antibiotics constitutes ...
Despite the adverse effects of microbial hazards on public health, major pharmaceutical firms have l...
A series of benzylidene hydrazides (1-20) was synthesized and tested, in vitro, for antibacterial, a...
ABSTRACT: In the present work, efforts have been made to model the antibacterial activity of 4-thiaz...
The inevitable consequence of the widespread use of antimicrobial agents has been the emergence of a...
A set of benzimidazole derivatives were tested for their inhibitory activities against the Gram-nega...
Some novel hydrazone derivatives 6a–o were synthesized from the key intermediate 4-Chloro-N-(2-hydra...