498-506A cobalt-catalyzed combinatorial synthesis of various β-phenylisoserinederivatives is described. This methodology is applied to a one-pot synthesis of pyrrolidine- containing α-hydroxyamidecore structure β-phenylisoserine-valinedipeptide isostere and α-acetyl- or α-hydroxyethyl- β -amino acid derivatives
In an effort to identify a new class of druglike HIV-1 protease inhibitors, four different stereopur...
In the present era, acquired immunodeficiency syndrome (AIDS) is the most fatal disorder for which n...
a. Synthese von Pyrrolidinbibliotheken an fester Phase mit Hilfe der Kombinatorischen Chemie; Charak...
A novel synthesis of pyrrolidine containing α-hydroxyamide core structures as inhibitors for HI...
N-Cinnamoyl-L-proline can be used as a template on which β-substituted phenylalanine and β...
A protocl has been developed for the generation of hydroxyethylamine peptide bond isosteres in a pol...
Infections with the human immunodeficiency virus, which inevitably lead to the development of AIDS, ...
Substituted bis-THF containing protease inhibitors were designed to optimize ligand-enzyme interacti...
Human Immunodeficiency Virus (HIV) is the causative agent of Acquired Immune Deficiency Syndrome (AI...
HIV-1 protease binds to its peptide/protein substrates in extended conformations. Therefore protease...
Infections with the human immunodeficiency virus, which inevitably lead to the development of AIDS, ...
The synthesis of a novel and versatile (2S,5S)-2,5-bis-[(1,1'-dimethylethoxy)carbonylamino]-1,6-diph...
The pyrrolidine nucleus is found in many biologically important natural products. This dissertation ...
This study has focused on the synthesis of truncated analogues of the hydroxyethylene dipeptide isos...
A series of novel HIV-1 protease inhibitors based on two pseudosymmetric dipeptide isosteres have be...
In an effort to identify a new class of druglike HIV-1 protease inhibitors, four different stereopur...
In the present era, acquired immunodeficiency syndrome (AIDS) is the most fatal disorder for which n...
a. Synthese von Pyrrolidinbibliotheken an fester Phase mit Hilfe der Kombinatorischen Chemie; Charak...
A novel synthesis of pyrrolidine containing α-hydroxyamide core structures as inhibitors for HI...
N-Cinnamoyl-L-proline can be used as a template on which β-substituted phenylalanine and β...
A protocl has been developed for the generation of hydroxyethylamine peptide bond isosteres in a pol...
Infections with the human immunodeficiency virus, which inevitably lead to the development of AIDS, ...
Substituted bis-THF containing protease inhibitors were designed to optimize ligand-enzyme interacti...
Human Immunodeficiency Virus (HIV) is the causative agent of Acquired Immune Deficiency Syndrome (AI...
HIV-1 protease binds to its peptide/protein substrates in extended conformations. Therefore protease...
Infections with the human immunodeficiency virus, which inevitably lead to the development of AIDS, ...
The synthesis of a novel and versatile (2S,5S)-2,5-bis-[(1,1'-dimethylethoxy)carbonylamino]-1,6-diph...
The pyrrolidine nucleus is found in many biologically important natural products. This dissertation ...
This study has focused on the synthesis of truncated analogues of the hydroxyethylene dipeptide isos...
A series of novel HIV-1 protease inhibitors based on two pseudosymmetric dipeptide isosteres have be...
In an effort to identify a new class of druglike HIV-1 protease inhibitors, four different stereopur...
In the present era, acquired immunodeficiency syndrome (AIDS) is the most fatal disorder for which n...
a. Synthese von Pyrrolidinbibliotheken an fester Phase mit Hilfe der Kombinatorischen Chemie; Charak...