Add to ORKG364-367A new series of five 1-(2′,4′-difluorophenyl)-3-(substituted phenyl)-1,3 propanediones from 2′,4′-difluorinated chalcones have been synthesized. All the compounds (20 mg/kg po) possess anti-inflammatory activity, as reflected by their ability to provide protection (70.00 - 93.00%) against carrageenan induced edema in rat paw. Standard indomethacin provided 79.00% protection at the same dose. The safety of these substituted propanediones are reflected by toxicity studies
Chalcone compounds are reported to have diverse biological activities such as antiviral, antimicrobi...
AbstractThe aim of this study was to synthesize three nitro substituted chalcones and to evaluate th...
The synthesis and pharmacological activity of 5-arylidene-2-imino-4- thiazolidinones (3a-8a) are des...
2064-2067A series of twelve 2',4'-difluorinated chalcones have been synthesized by Claisen-Schmidt c...
N-phenyl-5-substituted -aryl-3-p-(fluorophenyl) pyrazoles have been synthesized from cyclization of ...
Within the framework of our attempts to synthesize pleiotropic anti-inflammatory agents, we have syn...
A series of substituted derivatives containing the 1,4-benzodioxine or pyrrole nucleus are described...
A series of substituted 1,5-diarylpyrrole-3-alkoxyethyl ethers were previously synthesized and the p...
A series of substituted 1,5-diarylpyrrole-3-alkoxyethyl ethers were previously synthesized and the p...
A series of substituted 1,5-diarylpyrrole-3-alkoxyethyl ethers were previously synthesized and the p...
Arachidonic acid metabolism leads to the generation of key lipid mediators which play a fundamental ...
New 3-substituted [3, 4-dihydropyrimidinones]-Indolin-2-ones have been synthesized and tested for An...
Ibrahim Jantan,1,* Syed Nasir Abbas Bukhari,1,* Olayiwola A Adekoya,2 Ingebrigt Sylte3 1Drug and He...
Chalcone compounds and some n-hydroxychalcone compounds exhibit anti-inflammatory activity. Chalcone...
A series of some novel diarylsulfonylurea-chalcone hybrids synthesized in our earlier study as poten...
Chalcone compounds are reported to have diverse biological activities such as antiviral, antimicrobi...
AbstractThe aim of this study was to synthesize three nitro substituted chalcones and to evaluate th...
The synthesis and pharmacological activity of 5-arylidene-2-imino-4- thiazolidinones (3a-8a) are des...
2064-2067A series of twelve 2',4'-difluorinated chalcones have been synthesized by Claisen-Schmidt c...
N-phenyl-5-substituted -aryl-3-p-(fluorophenyl) pyrazoles have been synthesized from cyclization of ...
Within the framework of our attempts to synthesize pleiotropic anti-inflammatory agents, we have syn...
A series of substituted derivatives containing the 1,4-benzodioxine or pyrrole nucleus are described...
A series of substituted 1,5-diarylpyrrole-3-alkoxyethyl ethers were previously synthesized and the p...
A series of substituted 1,5-diarylpyrrole-3-alkoxyethyl ethers were previously synthesized and the p...
A series of substituted 1,5-diarylpyrrole-3-alkoxyethyl ethers were previously synthesized and the p...
Arachidonic acid metabolism leads to the generation of key lipid mediators which play a fundamental ...
New 3-substituted [3, 4-dihydropyrimidinones]-Indolin-2-ones have been synthesized and tested for An...
Ibrahim Jantan,1,* Syed Nasir Abbas Bukhari,1,* Olayiwola A Adekoya,2 Ingebrigt Sylte3 1Drug and He...
Chalcone compounds and some n-hydroxychalcone compounds exhibit anti-inflammatory activity. Chalcone...
A series of some novel diarylsulfonylurea-chalcone hybrids synthesized in our earlier study as poten...
Chalcone compounds are reported to have diverse biological activities such as antiviral, antimicrobi...
AbstractThe aim of this study was to synthesize three nitro substituted chalcones and to evaluate th...
The synthesis and pharmacological activity of 5-arylidene-2-imino-4- thiazolidinones (3a-8a) are des...