371-375Ascorbic acid treatment in arsenic trioxide treated rats increased arsenic excretion, inhibited lipid peroxidation, improved GSH status, regulated GSSG turnover and also restored glutathione-S-transferases activity in liver and kidney. Suitable mechanisms leading to ascorbic acid protection have been discussed. Upregulation of GSH dependent enzymes was found to be necessary for a protective effect. Protection is finally attributed to higher GSH levels observed in the liver and kidney of ascorbic acid and inorganic arsenic treated rats. It is also concluded that ascorbic acid protection is influenced by gender dependent factors. Arsenic poisoning is a global problem now. Gender differences need to be considered while applying therapeu...
Inorganic arsenic is a potent carcinogen and environmental pollutant. More than one hundred million ...
Arsenic consumption through drinking water is a worldwide major health problem. Management of arseni...
Arsenic is an environmental pollutant and its contamination in the drinking water is considered as a...
Isolated liver tissues of rat were loaded with trivalent arsenic and were exposed in presence and ab...
The patient of chronic arsenic toxicity shows oxidative stress. To overcome the oxidative stress, se...
Oxidative stress has been suggested to be a major cause of male reproductive failure. Here, we inves...
In this experiment thirty rats were exposed to 0 (Gr. I, healthy controls) or 10 ppm arsenic (sodium...
Induction of reactive oxygen species by arsenic and subsequent depletion of antioxidant cell defense...
Quest is still going on for a cheap, effective, and easily available remedy for chronic arsenic toxi...
The patient of chronic arsenic toxicity shows oxidative stress. To overcome the oxidative stress, se...
The effect of chronic As exposure in brain, the specific oxidants production and oxidative stress st...
Previous studies have shown that several factors may influence the methylation of inorganic arsenic ...
The livers of rats dosed acutely with As III developed a lipid vacuolation of the periportal area, a...
Background. Chronic exposure to arsenic is a major health concern consequent upon generation of exce...
Chronic exposure to toxic inorganic arsenic results in the adverse health effects including skin les...
Inorganic arsenic is a potent carcinogen and environmental pollutant. More than one hundred million ...
Arsenic consumption through drinking water is a worldwide major health problem. Management of arseni...
Arsenic is an environmental pollutant and its contamination in the drinking water is considered as a...
Isolated liver tissues of rat were loaded with trivalent arsenic and were exposed in presence and ab...
The patient of chronic arsenic toxicity shows oxidative stress. To overcome the oxidative stress, se...
Oxidative stress has been suggested to be a major cause of male reproductive failure. Here, we inves...
In this experiment thirty rats were exposed to 0 (Gr. I, healthy controls) or 10 ppm arsenic (sodium...
Induction of reactive oxygen species by arsenic and subsequent depletion of antioxidant cell defense...
Quest is still going on for a cheap, effective, and easily available remedy for chronic arsenic toxi...
The patient of chronic arsenic toxicity shows oxidative stress. To overcome the oxidative stress, se...
The effect of chronic As exposure in brain, the specific oxidants production and oxidative stress st...
Previous studies have shown that several factors may influence the methylation of inorganic arsenic ...
The livers of rats dosed acutely with As III developed a lipid vacuolation of the periportal area, a...
Background. Chronic exposure to arsenic is a major health concern consequent upon generation of exce...
Chronic exposure to toxic inorganic arsenic results in the adverse health effects including skin les...
Inorganic arsenic is a potent carcinogen and environmental pollutant. More than one hundred million ...
Arsenic consumption through drinking water is a worldwide major health problem. Management of arseni...
Arsenic is an environmental pollutant and its contamination in the drinking water is considered as a...