Add to ORKG113-117The role of biomolecule(s) from renal stone matrix in urolithiasis was investigated. The ability of a particular fraction (>10 kDa fraction) isolated from the EDTA extract of powdered human renal stones to influence calcium oxalate monohydrate (COM) crystal growth was studied. The most potent inhibitor of COM crystal growth obtained from >10 kDa fraction was purified by various chromatographic techniques and SDS-PAGE, etc. and was found to have a molecular mass of 36 kDa. The urine and serum samples obtained from normal persons were found to be more potent in inhibiting the growth of COM crystals as compared to the kidney-stone patients. Polyclonal antibodies were raised against this inhibitor and were employed to determine the conce...
Natural urinary macromolecular inhibitors: Attenuation of inhibitory activity by urate salts. The in...
Modulation by calcium of the inhibitor activity of naturally occurring urinary inhibitors. The possi...
Purpose Proteins constitute a major portion of the organic matrix of human calcium oxalate (CaOx...
Urinary stones are a common medical condition affecting over 10% of adults in the developed world. W...
Purpose: Proteins constitute a major portion of the organic matrix of human calcium oxalate (CaOx) r...
In order to obtain new insights into the relevance of inhibitors in whole urine by focusing on their...
The broad aim of the work presented in this thesis was to examine the relationship between the miner...
Partial biochemical and physicochemical characterization of organic macromolecules in urine from pat...
In order to obtain new insights into the relevance of inhibitors in whole urine by focusing on their...
The increasing number of patients suffering from urolithiasis represents one of the major challenges...
Reduced crystallization inhibition by urine from women with nephrolithiasis.BackgroundHuman urine is...
Background: The increasing number of patients suffering from urolithiasis represents one of the majo...
The influence of urinary macromolecules of nucleating calcium oxalate crystallites trapped in a matr...
Reduced crystallization inhibition by urine from men with nephrolithiasis.BackgroundHuman urine is k...
Immunochemistry of urinary calcium oxalate crystal growth inhibitor (CGI). Calcium oxalate crystal g...
Natural urinary macromolecular inhibitors: Attenuation of inhibitory activity by urate salts. The in...
Modulation by calcium of the inhibitor activity of naturally occurring urinary inhibitors. The possi...
Purpose Proteins constitute a major portion of the organic matrix of human calcium oxalate (CaOx...
Urinary stones are a common medical condition affecting over 10% of adults in the developed world. W...
Purpose: Proteins constitute a major portion of the organic matrix of human calcium oxalate (CaOx) r...
In order to obtain new insights into the relevance of inhibitors in whole urine by focusing on their...
The broad aim of the work presented in this thesis was to examine the relationship between the miner...
Partial biochemical and physicochemical characterization of organic macromolecules in urine from pat...
In order to obtain new insights into the relevance of inhibitors in whole urine by focusing on their...
The increasing number of patients suffering from urolithiasis represents one of the major challenges...
Reduced crystallization inhibition by urine from women with nephrolithiasis.BackgroundHuman urine is...
Background: The increasing number of patients suffering from urolithiasis represents one of the majo...
The influence of urinary macromolecules of nucleating calcium oxalate crystallites trapped in a matr...
Reduced crystallization inhibition by urine from men with nephrolithiasis.BackgroundHuman urine is k...
Immunochemistry of urinary calcium oxalate crystal growth inhibitor (CGI). Calcium oxalate crystal g...
Natural urinary macromolecular inhibitors: Attenuation of inhibitory activity by urate salts. The in...
Modulation by calcium of the inhibitor activity of naturally occurring urinary inhibitors. The possi...
Purpose Proteins constitute a major portion of the organic matrix of human calcium oxalate (CaOx...