Synthesis of pyrazole and isoxazole in triethanolamine medium.

532-534Reactions of 2′-hydroxy chalcone dibromides 2a-l with phenyl hydrazine and hydrazine hydrate afford pyrazoles 1a-l and with hydroxylamine hydrochloride give isoxazoles 5a-f in triethanolamine medium. Similarly reaction of β-diketone 3b-e with phenyl hydrazine and hydrazine hydrate in TEA gives pyrazoles 4a-l in high yield in shorter time. The products are confirmed by their m.p., m.m.p., chemical analysis and IR, ¹H NMR spectral data