Transcatheter valve-in-valve implantation versus reoperative conventional aortic valve replacement: a systematic review

Phan, Kevin
Zhao, Dong-Fang
Wang, Nelson
Huo, Ya Ruth
Di Eusanio, Marco
Yan, Tristan D

Open PDF

Open link

Publication date

January 2016

DOI

10.3978/j.issn.2072-1439.2016.01.44

Language

English

Abstract

Transcatheter valve-in-valve (VIV) implantation for degenerated aortic bioprostheses has emerged as a promising alternative to redo conventional aortic valve replacement (cAVR). However there are concerns surrounding the efficacy and safety of VIV. This systematic review aims to compare the outcomes and safety of transcatheter VIV implantation with redoes cAVR. Six databases were systematically searched. A total of 18 relevant studies (823 patients) were included. Pooled analysis demonstrated VIV achieved significant improvements in mean gradient (38 mmHg preoperatively to 15.2 mmHg postoperatively, P<0.001) and peak gradient (59.2 to 23.2 mmHg, P=0.0003). These improvements were similar to the outcomes achieved by cAVR. The incidence of mo...