The livers of rats given ethanol for 5 weeks showed marked structural alterations of hepatocytes of acinar zone 3 including mitochondrial pleomorphism, increased smooth endoplasmic reticulum and deposition of small (less than 0.5 micron) lipid droplets. In addition, apoptotic bodies involving altered parenchymal cells were frequently observed, together with prominent mononuclear infiltrates adjacent to the terminal hepatic veins. It is suggested that 'age' of liver cells may play a role in the preferential perivenular localization of early ethanol-induced liver damage
(a) disruption of hepatic architecture (X200). (b) Mononuclear cell infiltration between hepatic lob...
Chronic ethanol feeding selectively impairs the translocation of cytosol GSH into the mitochondrial ...
The aim of this study was to investigate in vitro in a human hepatoblastoma cell line, Hep G2, the e...
The livers of rats given ethanol for 5 weeks showed marked structural alterations of hepatocytes of ...
The present study was conducted to evaluate if the increased rate of apoptosis previously reported i...
The aim of the present study was to determine if data on the number and acinar distribution of apopt...
Acute ethanol administration partially inhibits DNA and protein syntheses during liver regeneration ...
Ethanol, also known as ethyl alcohol, pure alcohol, and alcohol, is a toxic, volatile, flammable, an...
Abstract — Aims: In-vivo and in-vitro studies have shown that ethanol induces hepatocyte damage. The...
The aim of this study was to morphologicall investigation of alcohol-induced hepatocyte apoptosis an...
<p>Five animals per group and three H&E sections per animal were analysed. Images and data from the ...
It is generally agreed that the deleterious pathophysiological effects of ethanol are caused, at lea...
Ultrastructural observations of principal cells of the epithelium lining of the proximal caput epidi...
<p>(A1) Histopathological changes were not observed in rats received control liquid diet. (A2), (A3)...
Multiple lines of experimental evidence demonstrate that chronic alcohol consumption causes mitochon...
(a) disruption of hepatic architecture (X200). (b) Mononuclear cell infiltration between hepatic lob...
Chronic ethanol feeding selectively impairs the translocation of cytosol GSH into the mitochondrial ...
The aim of this study was to investigate in vitro in a human hepatoblastoma cell line, Hep G2, the e...
The livers of rats given ethanol for 5 weeks showed marked structural alterations of hepatocytes of ...
The present study was conducted to evaluate if the increased rate of apoptosis previously reported i...
The aim of the present study was to determine if data on the number and acinar distribution of apopt...
Acute ethanol administration partially inhibits DNA and protein syntheses during liver regeneration ...
Ethanol, also known as ethyl alcohol, pure alcohol, and alcohol, is a toxic, volatile, flammable, an...
Abstract — Aims: In-vivo and in-vitro studies have shown that ethanol induces hepatocyte damage. The...
The aim of this study was to morphologicall investigation of alcohol-induced hepatocyte apoptosis an...
<p>Five animals per group and three H&E sections per animal were analysed. Images and data from the ...
It is generally agreed that the deleterious pathophysiological effects of ethanol are caused, at lea...
Ultrastructural observations of principal cells of the epithelium lining of the proximal caput epidi...
<p>(A1) Histopathological changes were not observed in rats received control liquid diet. (A2), (A3)...
Multiple lines of experimental evidence demonstrate that chronic alcohol consumption causes mitochon...
(a) disruption of hepatic architecture (X200). (b) Mononuclear cell infiltration between hepatic lob...
Chronic ethanol feeding selectively impairs the translocation of cytosol GSH into the mitochondrial ...
The aim of this study was to investigate in vitro in a human hepatoblastoma cell line, Hep G2, the e...