Add to ORKG[reaction: see text] Reaction of hindered lithium amides with readily available (enantiopure) terminal epoxides gives 2-ene-1,4-diols via carbenoid dimerization of the corresponding alpha-lithiated epoxides. D-Mannitol and D-iditol were synthesized using this method in three steps from (S)-tritylglycidyl ether
The scope and limitations of lithium 2,2,6,6-tetramethylpiperidide (LTMP)-modified reductive alkylat...
(R)-2-Cyclohexen-1-ol and (R)-2-cyclooctene-1-ol have been prepared in very good ee using R,R-homoch...
The aldol addition is one of the most important carbon-carbon bond-forming reactions in chemical syn...
Enantioselective generation and intermolecular trapping of a lithium carbenoid occurs in the reactio...
Deprotonation of terminal epoxides and aziridines with organolithium/ diamine combinations or lithiu...
The title compd. (I) was prepd. from D-mannitol by isopropylidenation, Pb(OAc)4 oxidn., redn., Grign...
Enantiomerically pure terminal 1,2-diols are important synthetic intermediates.1 A number of synthet...
A screen of external chiral ligands has led to enantioselective organolithium-induced alkylative dou...
Although the lithium base-induced β-elimination of epoxides to allylic alcohols is a well-known reac...
E-Alkenes (including arylated alkenes, dienes, and allylsilanes) are efficiently prepared by alpha-d...
(Chemical Equation Presented) Effective discrimination: Efficient lithium amide-induced terminal epo...
Dihydrofuran and dihydropyran epoxides undergo a stereospecific alkylative double ring-opening with ...
Homochiral (E)-enamides derived from (S)-4-phenyl-5,5-dimethyl-oxazolidin-2-one undergo highly diast...
Titanium tetrachloride promoted reaction of trimethylsilyl enol ethers with ethylene oxide affords h...
The synthesis and enantioselective α-deprotonation - double ring opening of 6,7-epoxy-8-azabicyclo[3...
The scope and limitations of lithium 2,2,6,6-tetramethylpiperidide (LTMP)-modified reductive alkylat...
(R)-2-Cyclohexen-1-ol and (R)-2-cyclooctene-1-ol have been prepared in very good ee using R,R-homoch...
The aldol addition is one of the most important carbon-carbon bond-forming reactions in chemical syn...
Enantioselective generation and intermolecular trapping of a lithium carbenoid occurs in the reactio...
Deprotonation of terminal epoxides and aziridines with organolithium/ diamine combinations or lithiu...
The title compd. (I) was prepd. from D-mannitol by isopropylidenation, Pb(OAc)4 oxidn., redn., Grign...
Enantiomerically pure terminal 1,2-diols are important synthetic intermediates.1 A number of synthet...
A screen of external chiral ligands has led to enantioselective organolithium-induced alkylative dou...
Although the lithium base-induced β-elimination of epoxides to allylic alcohols is a well-known reac...
E-Alkenes (including arylated alkenes, dienes, and allylsilanes) are efficiently prepared by alpha-d...
(Chemical Equation Presented) Effective discrimination: Efficient lithium amide-induced terminal epo...
Dihydrofuran and dihydropyran epoxides undergo a stereospecific alkylative double ring-opening with ...
Homochiral (E)-enamides derived from (S)-4-phenyl-5,5-dimethyl-oxazolidin-2-one undergo highly diast...
Titanium tetrachloride promoted reaction of trimethylsilyl enol ethers with ethylene oxide affords h...
The synthesis and enantioselective α-deprotonation - double ring opening of 6,7-epoxy-8-azabicyclo[3...
The scope and limitations of lithium 2,2,6,6-tetramethylpiperidide (LTMP)-modified reductive alkylat...
(R)-2-Cyclohexen-1-ol and (R)-2-cyclooctene-1-ol have been prepared in very good ee using R,R-homoch...
The aldol addition is one of the most important carbon-carbon bond-forming reactions in chemical syn...