The reductive alkylation of 3,4-disubstituted pyridines is reported using either sodium in ammonia or ammonia free conditions (Na, naphthalene, THF). This partial reduction process works cleanly and efficiently giving good yields of highly functionalised dihydropyridine templates. Radical cyclisation reactions were performed on these dihydropyridines and gave fused 2- and 3-ring heterocycles with defined stereochemistry
Tandem reactions for the efficient synthesis of multifunctionalized 1,2,3,4-tetrahydropyridines, 2,3...
Herein we report a practical protocol for the visible-lightinduced regiodivergent radical hydropyrid...
Herein, we report a new process for the synthesis of highly functionalized pyridines based on a tand...
The reductive alkylation of 3,4-disubstituted pyridines is reported using either sodium in ammonia o...
The partial reduction of electron-deficient pyridines is described herein. Mono- and disubstituted p...
This paper reports a study into the partial reduction of N-alkylpyridinium salts together with subse...
The phosphine-catalyzed synthesis of 1,2-dihydropyridines via an alkyne isomerization/electrocycliza...
The copper-catalyzed synthesis of functionalized pyridines and partially reduced pyridine derivative...
The partial reduction of a series of heterocycles in THF is described. By adding amine 3 as a proton...
3,5-Dicarbamoyl-1,4-dihydropyridines were prepared in high yields using a green protocol by reductio...
Recently in the Ellman and Bergman groups a method was discovered for preparing 1,2-dihydropyridines...
Facile conversion of 2-piperidones and 2-pyrrolidones into 2-cyano-3-iodo piperidines or pyrrolidine...
The pyridine heterocycle continues to play a vital role in the development of human medicines. More ...
The pyridine heterocycle continues to play a vital role in the development of human medicines. More ...
This paper describes the transformation of flat N-containing aromatic compounds (pyridines and quino...
Tandem reactions for the efficient synthesis of multifunctionalized 1,2,3,4-tetrahydropyridines, 2,3...
Herein we report a practical protocol for the visible-lightinduced regiodivergent radical hydropyrid...
Herein, we report a new process for the synthesis of highly functionalized pyridines based on a tand...
The reductive alkylation of 3,4-disubstituted pyridines is reported using either sodium in ammonia o...
The partial reduction of electron-deficient pyridines is described herein. Mono- and disubstituted p...
This paper reports a study into the partial reduction of N-alkylpyridinium salts together with subse...
The phosphine-catalyzed synthesis of 1,2-dihydropyridines via an alkyne isomerization/electrocycliza...
The copper-catalyzed synthesis of functionalized pyridines and partially reduced pyridine derivative...
The partial reduction of a series of heterocycles in THF is described. By adding amine 3 as a proton...
3,5-Dicarbamoyl-1,4-dihydropyridines were prepared in high yields using a green protocol by reductio...
Recently in the Ellman and Bergman groups a method was discovered for preparing 1,2-dihydropyridines...
Facile conversion of 2-piperidones and 2-pyrrolidones into 2-cyano-3-iodo piperidines or pyrrolidine...
The pyridine heterocycle continues to play a vital role in the development of human medicines. More ...
The pyridine heterocycle continues to play a vital role in the development of human medicines. More ...
This paper describes the transformation of flat N-containing aromatic compounds (pyridines and quino...
Tandem reactions for the efficient synthesis of multifunctionalized 1,2,3,4-tetrahydropyridines, 2,3...
Herein we report a practical protocol for the visible-lightinduced regiodivergent radical hydropyrid...
Herein, we report a new process for the synthesis of highly functionalized pyridines based on a tand...