Add to ORKGEpithelial histocompatibility locus antigen (HLA) class II expression was studied to evaluate its induction by mucosal mononuclear cells in inflammatory bowel disease and to characterise the responsible cytokine. Unstimulated cells of the HT-29 epithelial cell line did not produce class II molecules. After being stimulated with the mitogenic lectin phytohaemagglutinin mucosal mononuclear cells released a cytokine that induced epithelial HLA-DR expression. The cytokine had the physicochemical and immunological characteristics of interferon-gamma, and no additional cytokines were detected
The etiology of inflammatory bowel disease is still not definitely clarified. Inflammatory bowel dis...
The pathogenesis of inflammatory bowel diseases (IBDs) seems to involve a primary defect in one or m...
The pathogenesis of inflammatory bowel diseases (IBDs) seems to involve a primary defect in one or m...
Epithelial histocompatibility locus antigen (HLA) class II expression was studied to evaluate its in...
Eighty four colonic biopsy specimens were obtained from patients with ulcerative colitis, Crohn's di...
Eighty four colonic biopsy specimens were obtained from patients with ulcerative colitis, Crohn's di...
The expression of HLA-DR and HLA-A,B,C antigens by human colonic epithelium has been examined in tis...
The objectives of this study were to activate human colonic intraepithelial lymphocytes at the trans...
The induction of T cell responses requires recognition of antigens in association with class II majo...
IEL are a unique population of cells. Their function remains largely unknown. Human colonic IEL were...
We have elucidated the distribution of I2 (HLA-DR) antigen in control and inflammatory bowel disease...
The major histocompatibility complex (MHC) class II antigens were originally described to be express...
To explore the auto-reactive potential of cells infiltrating the gut mucosa in idiopathic chronic in...
The major histocompatibility complex (MHC) class II antigens were originally described to be express...
Thirty years of research on the role of immune-mediated cytotoxic activity in the tissue injury of i...
The etiology of inflammatory bowel disease is still not definitely clarified. Inflammatory bowel dis...
The pathogenesis of inflammatory bowel diseases (IBDs) seems to involve a primary defect in one or m...
The pathogenesis of inflammatory bowel diseases (IBDs) seems to involve a primary defect in one or m...
Epithelial histocompatibility locus antigen (HLA) class II expression was studied to evaluate its in...
Eighty four colonic biopsy specimens were obtained from patients with ulcerative colitis, Crohn's di...
Eighty four colonic biopsy specimens were obtained from patients with ulcerative colitis, Crohn's di...
The expression of HLA-DR and HLA-A,B,C antigens by human colonic epithelium has been examined in tis...
The objectives of this study were to activate human colonic intraepithelial lymphocytes at the trans...
The induction of T cell responses requires recognition of antigens in association with class II majo...
IEL are a unique population of cells. Their function remains largely unknown. Human colonic IEL were...
We have elucidated the distribution of I2 (HLA-DR) antigen in control and inflammatory bowel disease...
The major histocompatibility complex (MHC) class II antigens were originally described to be express...
To explore the auto-reactive potential of cells infiltrating the gut mucosa in idiopathic chronic in...
The major histocompatibility complex (MHC) class II antigens were originally described to be express...
Thirty years of research on the role of immune-mediated cytotoxic activity in the tissue injury of i...
The etiology of inflammatory bowel disease is still not definitely clarified. Inflammatory bowel dis...
The pathogenesis of inflammatory bowel diseases (IBDs) seems to involve a primary defect in one or m...
The pathogenesis of inflammatory bowel diseases (IBDs) seems to involve a primary defect in one or m...