C23-carbazole alkaloids from the bark of Murraya koenigii (L.) Spreng

Murraya koenigii (Rutaceae), locally known as curry leaf tree, is a medicinally important herb of Indian origin and now is widely distributed throughout southern Asia. The bark of Malayan Murraya koenigii was investigated for phytochemical content. The isolation of chemical constituents from its hexane extract was carried out by using various chromatographic techniques. Spectroscopic methods, including NMR, IR, UV, MS spectra data, were used for the structural characterization. Four C23-carbazole alkaloids were isolated and identified as mahanimbine, murrayamine-J, murrayazolinol and bicyclomahanimbine