Evaluation of conventional renal function tests in patients with ?-thalassemia major using deferasirox

?-thalassemia major is characterised by grossly defective synthesis of haemoglobin A along with increased production of haemoglobin F, impaired red blood cells production and increased haemolysis of the defective red blood cells. Affected individuals are dependent on repeated blood transfusions and iron chelating therapy. Patients on blood transfusion may develop complications related to iron overload and adverse effects of chelating agent which has harmful effects on many organs in the body including the kidneys. The present study was aimed to investigate renal functions in paediatric patients with transfusion dependent ?-thalassemia major using deferasirox. This study consisted of two groups of ?-thalassemia patient