Add to ORKGA concise approach to cis-2,5-disubstituted pyrrolidines is reported, which relies upon N-tert-butoxycarbonylmethyl substitution in a substrate derived from pyroglutamic acid. The method is especially noteworthy since a significant improvement in the conditions for a key Lawesson's reaction have been established. Regioselective enolate generation and alkylation permits extension of the C-5 side chain. © 2003 Elsevier Ltd. All rights reserved
This thesis describes the synthesis of a family of amino acids containing a ketone functionalised si...
Palladium(II)-catalyzed aerobic oxidative cyclization of alkenes with tethered <i>tert</i>-butanesul...
In the past few decades, an extensive family of structurally intriguing and biologically active pyrr...
A concise approach to cis-2,5-disubstituted pyrrolidines is reported, which relies upon N-tert-butox...
A direct and versatile route enabling the regio- and diastereoselective synthesis of 2,5-disubstitut...
Methodology for the diastereoselective synthesis of 2,5-disubstituted pyrrolidines by reduction of e...
A direct and versatile route for the reliable synthesis of trans-2,5-disubstituted pyrrolidines from...
The synthesis and utility of the 3,3-dimethyl-5-substituted-2-pyrrolidinone 'Quat' chiral auxiliary ...
The (+/-)-cis-5-arylcarbamoyl-2-ethoxycarbonylpyrrolidines 6a-g were firstly synthesized in 53-64% y...
A practical, enantioselective synthesis of <i>cis</i>-2,5-disubstituted pyrrolidine is described. Ap...
[reaction: see text] The partial reduction of electron-deficient 2,5-disubstituted pyrroles has been...
A regioselective synthesis of pyrroles has been devised through the cycloaddition of 1,3-oxazolium-5...
5-trans-Substituted 2-pyrrolidinones 6a, 6c and 6d and 5,5-disubstituted 2-pyrrolidinones 6e-k were ...
A regioselective synthesis of pyrroles has been devised through the cycloaddition of 1,3-oxazolium-5...
The partial reduction of N-Boc pyrroles has been explored giving stereoselective routes to disubstit...
This thesis describes the synthesis of a family of amino acids containing a ketone functionalised si...
Palladium(II)-catalyzed aerobic oxidative cyclization of alkenes with tethered <i>tert</i>-butanesul...
In the past few decades, an extensive family of structurally intriguing and biologically active pyrr...
A concise approach to cis-2,5-disubstituted pyrrolidines is reported, which relies upon N-tert-butox...
A direct and versatile route enabling the regio- and diastereoselective synthesis of 2,5-disubstitut...
Methodology for the diastereoselective synthesis of 2,5-disubstituted pyrrolidines by reduction of e...
A direct and versatile route for the reliable synthesis of trans-2,5-disubstituted pyrrolidines from...
The synthesis and utility of the 3,3-dimethyl-5-substituted-2-pyrrolidinone 'Quat' chiral auxiliary ...
The (+/-)-cis-5-arylcarbamoyl-2-ethoxycarbonylpyrrolidines 6a-g were firstly synthesized in 53-64% y...
A practical, enantioselective synthesis of <i>cis</i>-2,5-disubstituted pyrrolidine is described. Ap...
[reaction: see text] The partial reduction of electron-deficient 2,5-disubstituted pyrroles has been...
A regioselective synthesis of pyrroles has been devised through the cycloaddition of 1,3-oxazolium-5...
5-trans-Substituted 2-pyrrolidinones 6a, 6c and 6d and 5,5-disubstituted 2-pyrrolidinones 6e-k were ...
A regioselective synthesis of pyrroles has been devised through the cycloaddition of 1,3-oxazolium-5...
The partial reduction of N-Boc pyrroles has been explored giving stereoselective routes to disubstit...
This thesis describes the synthesis of a family of amino acids containing a ketone functionalised si...
Palladium(II)-catalyzed aerobic oxidative cyclization of alkenes with tethered <i>tert</i>-butanesul...
In the past few decades, an extensive family of structurally intriguing and biologically active pyrr...