Osteoarthritis (degenerative joint disease) is the commonest form of arthritis. It is a leading cause of disability and its prevalence continues to rise, representing a considerable economic burden. Insights into the pathogenesis of osteoarthritis at genetic, molecular, tissue and clinical levels may expand the currently limited therapeutic options. This review will summarize our current understanding of the major factors responsible for the initiation and progression of osteoarthritis including genetics, biomechanics and patient-specific features such as age, gender and body mass index. It will also outline the key pathogenic mechanisms and histological features of osteoarthritis. © 2010 Elsevier Ltd
Introduction: Although they do not endanger the life of the individual, the major symptoms of osteoa...
Osteoarthritis afflicts millions of individuals across the world resulting in impaired quality of li...
Osteoarthritis (OA) is a degenerative joint disease and the most common form of arthritis. Character...
Osteoarthritis (OA) is a growing public health problem across the globe, affecting more than half of...
Osteoarthritis, a degenerative joint disease, is the most disabling condition of the Western world. ...
Introduction Osteoarthritis (OA) is one of the most common forms of arthritis. There is accumulating...
Osteoarthritis (OA) is a condition with high prevalence worldwide. OA affects not only the articular...
Introduction Osteoarthritis (OA) is one of the most common forms of arthritis. There is accumulating...
Osteoarthritis (OA) is a growing public health problem across the globe, affecting more than half of...
Although osteoarthritis (OA) is the most common musculoskeletal condition that causes significant he...
Osteoarthritis (OA) is the most common form of arthritis. Two-thirds of the population older than 60...
Osteoarthritis has developed into the most common chronic disease in the highly industrialized natio...
markdownabstract__Abstract__ Osteoarthritis (OA) is an invalidating disease characterized by prog...
Osteoarthritis (OA) is the most common form of arthritis and is a leading cause of pain and disabili...
Osteoarthritis is a pathological lesion of the joints, characterized by structural changes in the ar...
Introduction: Although they do not endanger the life of the individual, the major symptoms of osteoa...
Osteoarthritis afflicts millions of individuals across the world resulting in impaired quality of li...
Osteoarthritis (OA) is a degenerative joint disease and the most common form of arthritis. Character...
Osteoarthritis (OA) is a growing public health problem across the globe, affecting more than half of...
Osteoarthritis, a degenerative joint disease, is the most disabling condition of the Western world. ...
Introduction Osteoarthritis (OA) is one of the most common forms of arthritis. There is accumulating...
Osteoarthritis (OA) is a condition with high prevalence worldwide. OA affects not only the articular...
Introduction Osteoarthritis (OA) is one of the most common forms of arthritis. There is accumulating...
Osteoarthritis (OA) is a growing public health problem across the globe, affecting more than half of...
Although osteoarthritis (OA) is the most common musculoskeletal condition that causes significant he...
Osteoarthritis (OA) is the most common form of arthritis. Two-thirds of the population older than 60...
Osteoarthritis has developed into the most common chronic disease in the highly industrialized natio...
markdownabstract__Abstract__ Osteoarthritis (OA) is an invalidating disease characterized by prog...
Osteoarthritis (OA) is the most common form of arthritis and is a leading cause of pain and disabili...
Osteoarthritis is a pathological lesion of the joints, characterized by structural changes in the ar...
Introduction: Although they do not endanger the life of the individual, the major symptoms of osteoa...
Osteoarthritis afflicts millions of individuals across the world resulting in impaired quality of li...
Osteoarthritis (OA) is a degenerative joint disease and the most common form of arthritis. Character...